SCHEMBL1448849

SCHEMBL1448849

CCCCCCCCCc1ccc(S(=O)(=O)[O-])cc1.[Na+]

nearest known ligand 0.66

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 3/20 0.66
ADORA3 known ✓ P0DMS8 2/20 0.53
PTGS1 known ✓ P23219 1/20 0.53
ADORA2A known ✓ P29274 1/20 0.53
PTGS2 known ✓ P35354 1/20 0.53
CA12 known ✓ O43570 1/20 0.52
CA1 known ✓ P00915 1/20 0.52
LMNA P02545 3/20 0.59
HIF1A Q16665 2/20 0.59
HTT P42858 2/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
TSHR P16473 1/20 0.59
CYP2C19 P33261 1/20 0.59
KCNH2 Q12809 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
NR1I2 O75469 1/20 0.55
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
TACR2 P21452 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457843 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL11057835 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL11450888 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL446403 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL149982 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL3860078 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL11059907 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL11712823 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL3853262 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6
SCHEMBL28490846 1.00 CA2 (0.66) CA2LMNAHIF1AHTTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7910500-B2 Fiber treatment agent, fiber treated with such fiber treatment agent, fiber fabric, laminate and method for treating fiber IDEMITSU TECHNOFINE CO., LTD. (JP) 2011-03-22 US disclosed
US-20100215957-A1 FIBER CROSS-LINKED BODY AND MANUFACTURING METHOD OF FIBER CROSS-LINKED BODY IDEMITSU TECHNOFINE CO., LTD. (JP) 2010-08-26 US disclosed
EP-1208162-B1 CHEMICALLY MODIFIED FILLERS AND POLYMERIC COMPOSITIONS CONTAINING SAME PPG IND OHIO INC (US) 2010-04-28 EP disclosed
US-7704552-B2 Process for producing chemically treated amorphous precipitated silica PPG INDUSTRIES OHIO, INC. (US) 2010-04-27 US disclosed
US-7687107-B2 Process for producing chemically modified amorphous precipitated silica PPG INDUSTRIES OHIO, INC. (US) 2010-03-30 US disclosed
EP-1208163-B1 CHEMICALLY TREATED FILLERS AND POLYMERIC COMPOSITIONS CONTAINING SAME PPG IND OHIO INC (US) 2009-08-05 EP disclosed
US-20090149095-A1 Fiber Treatment Agent, Fiber Treated With Such Fiber Treatment Agent, Fiber Fabric, Laminate And Method For Treating Fiber IDEMITSU TECHNOFINE CO., LTD. (JP) 2009-06-11 US disclosed
EP-1867778-A1 FIBER TREATMENT AGENT, FIBER TREATED WITH SUCH FIBER TREATMENT AGENT, FIBER FABRIC, LAMINATE AND METHOD FOR TREATING FIBER Idemitsu Technofine Co. Ltd (JP) 2007-12-19 EP disclosed
EP-1208165-B1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG IND OHIO INC (US) 2007-12-19 EP disclosed
EP-1208164-B1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG IND OHIO INC (US) 2007-10-24 EP disclosed
WO-2001012734-A1 CHEMICALLY MODIFIED FILLERS AND POLYMERIC COMPOSITIONS CONTAINING SAME PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO disclosed
WO-2001012733-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO disclosed
US-5369118-A N-alkyl-lactams as crystallization inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1994-11-29 US disclosed
US-5328693-A N-allyl-lactams as crystallization inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
US-5206225-A ALKYLCARBOXYLIC ACID DIMETHYLAMIDES AS CRYSTALLIZATION INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
US-5053421-A Fungicidal aqueous spray liquid BAYER AKTIENGESELLSCHAFT (DE) 1991-10-01 US disclosed
US-4704414-A WATER INSOLUBLE SILICON-CONTAINING POLYSULFIDES DEGUSSA AKTIENGESELLSCHAFT (DE) 1987-11-03 US disclosed
US-4508633-A CRYSTALLINE TYPE A ZEOLITE DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-04-02 US disclosed
US-4500348-A Oil-in-water emulsions, and their use BAYER AKTIENGESELLSCHAFT (DE) 1985-02-19 US disclosed
US-3984245-A SILVER HALIDE EMULSION, DEVELOPMENT INHIBITOR, COLLOID, MULTILAYER FUJI PHOTO FILM CO., LTD. (JA) 1976-10-05 US disclosed