Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707718 | 0.98 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| Water SCHEMBL15066604 | 0.98 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| Water SCHEMBL25355214 | 0.96 | NR1H2 (0.35) | NR1H2NR1H3RORCNR1I2 | |
| SCHEMBL985526 | 0.96 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| Lithium Ion SCHEMBL1451369 | 0.94 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| SCHEMBL7148800 | 0.94 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| SCHEMBL1451577 | 0.94 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| Silver SCHEMBL1450737 | 0.94 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| Potassium Ion SCHEMBL16669355 | 0.94 | NR1H2 (0.36) | NR1H2NR1H3RORCNR1I2 | |
| SCHEMBL29831166 | 0.93 | NR1H2 (0.33) | NR1H2NR1H3RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 994 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12601705-B2 | Sensor for measuring ionized magnesium | INSTRUMENTATION LABORATORY COMPANY (US) | 2026-04-14 | — | — | US | claimed |
| US-20250361525-A1 | AAV VECTORS FOR GENE EDITING | SCRIBE THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | claimed |
| EP-4476537-B1 | SENSOR FOR MEASURING IONIZED MAGNESIUM | INSTR LABORATORY CO (US) | 2025-10-29 | — | — | EP | claimed |
| US-20250195631-A1 | ANTIGEN DELIVERING SALMONELLA FOR USE AS A TUMOR HOMING BEACON TO REFOCUS PREEXISTING, VACCINE GENERATED T CELLS TO COMBAT CANCER | UNIVERSITY OF MASSACHUSETTS | 2025-06-19 | — | — | US | claimed |
| US-12318437-B2 | Vaccine formulations comprising preservative | BIOLOGICAL E LIMITED (IN) | 2025-06-03 | — | — | US | claimed |
| US-20250152693-A1 | Neisseria Meningitidis Vaccine | SANOFI PASTEUR INC. (US) | 2025-05-15 | — | — | US | claimed |
| CN-119905278-A | Hepatitis B research path generation method and device based on CR-HepB platform and electronic equipment | 首都医科大学附属北京友谊医院 | 2025-04-29 | — | — | CN | claimed |
| EP-4536286-A1 | AAV VECTORS FOR GENE EDITING | Scribe Therapeutics Inc. (US) | 2025-04-16 | — | — | EP | claimed |
| EP-4322949-B1 | ISOQUINOLINE DERIVATIVES FOR USE AS ANTIVIRAL AND ANTITUMOUR AGENTS | RDP PHARMA AG (CH) | 2025-03-19 | — | — | EP | claimed |
| EP-4499805-A1 | ANTIGEN DELIVERING SALMONELLA FOR USE AS A TUMOR HOMING BEACON TO REFOCUS PREEXISTING, VACCINE GENERATED T CELLS TO COMBAT CANCER | University Of Massachusetts (US) | 2025-02-05 | — | — | EP | claimed |
| CN-115651010-A | Reactive type low-heat-generation flame-retardant antioxidant auxiliary agent, preparation method and application thereof, and vulcanized rubber | 株洲时代新材料科技股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| WO-2022224966-A1 | LIQUID SEXTUPLE VACCINE COMPOSITION | ＫＭバイオロジクス株式会社 | 2022-10-27 | — | — | WO | claimed |
| WO-2022162397-A1 | TRANSDERMAL VACCINE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-08-04 | — | — | WO | claimed |
| WO-2022162398-A1 | VACCINE COMPOSITIONS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-08-04 | — | — | WO | claimed |
| EP-4035676-A1 | VACCINE COMPOSITIONS | Oxford University Innovation Limited (GB) | 2022-08-03 | — | — | EP | claimed |
| EP-4035673-A1 | TRANSDERMAL VACCINE | Oxford University Innovation Limited (GB) | 2022-08-03 | — | — | EP | claimed |
| WO-2022152993-A1 | DETECTION OF SHORT-CIRCUIT FAULTS BETWEEN STATOR COILS OF AN ELECTRIC MACHINE | SAFRAN ELECTRICAL & POWER (FR) | 2022-07-21 | — | — | WO | claimed |
| WO-2022125843-A1 | AAV VECTORS FOR GENE EDITING | SCRIBE THERAPEUTICS INC. (US) | 2022-06-16 | — | — | WO | claimed |
| US-11193915-B2 | Composite material for the detection of chemical species | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-12-07 | — | — | US | claimed |
| US-20190017978-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2019-01-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601705-B2 | Sensor for measuring ionized magnesium | MAG, S100B, S100P | NR1H2 2667/4885NR1H3 2850/4885RORC 4470/4885 |
| US-20250152693-A1 | Neisseria Meningitidis Vaccine | B3GNT2, MLEC, MAG | NR1H2 2683/4885NR1H3 2657/4885RORC 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.