SCHEMBL14616012

SCHEMBL14616012

CC(C)(CCN)OCCC(C)(C)OCCN

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14450206 0.88 KIF11 (0.30) KIF11
SCHEMBL17210648 0.88 KIF11 (0.30) KIF11
SCHEMBL3175803 0.87
SCHEMBL13202552 0.86
SCHEMBL18744473 0.86
SCHEMBL10187601 0.86
SCHEMBL16348115 0.86
SCHEMBL368863 0.86 ALDH1A1 (0.35)
SCHEMBL29300445 0.86 ODC1 (0.35)
SCHEMBL26751242 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024016000-A2 EIF4A INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-18 WO disclosed
US-20230040208-A1 ELECTROCHROMIC APERTURE AND MANUFACTURING METHOD THEREFOR, AND LENS MODULE HAVING ELECTROCHROMIC APERTURE Shenzhen Guangyi Tech Co., Ltd. (CN) 2023-02-09 US disclosed
EP-4092038-A1 OPIOID AGONIST PEPTIDES AND USES THEREOF Protagonist Therapeutics, Inc. (US) 2022-11-23 EP disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 WO disclosed
US-10669538-B2 Templated molecules and methods for using such molecules NUEVOLUTION A/S (DK) 2020-06-02 US disclosed
US-10308774-B2 Polycarbonate containing compounds and methods related thereto VANDERBILT UNIVERSITY (US) 2019-06-04 US disclosed
US-9758671-B2 Strain-promoted crosslinking of PEG-based hydrogels via copper-free cycloaddition BECKER MATTHEW (US) 2017-09-12 US disclosed
US-20170198283-A1 TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES NUEVOLUTION A/S (DK) 2017-07-13 US disclosed
US-20170182173-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2017-06-29 US disclosed
US-9688980-B2 Templated molecules and methods for using such molecules NUEVOLUTION (DK) 2017-06-27 US disclosed
US-20170166710-A1 Polycarbonate Containing Compounds and Methods Related Thereto UNIV VANDERBILT (US) 2017-06-15 US disclosed
US-20170119907-A1 Targeted Therapeutics MEDIVATION TECHNOLOGIES, INC. (US) 2017-05-04 US disclosed
US-9637592-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-05-02 US disclosed
US-20170107255-A1 APELIN POLYPEPTIDES AMGEN INC. (US) 2017-04-20 US disclosed
WO-2017019832-A1 METHODS AND COMPOSITIONS USING REPAIR CELLS AND CATIONIC DYES MEDIVATION TECHNOLOGIES, INC. (US) 2017-02-02 WO disclosed
WO-2016050210-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR 厦门赛诺邦格生物科技有限公司 2016-04-07 WO disclosed
US-20070031499-A1 Readily shapeable xerogels having controllably delayed swelling properties AKINA, INC. 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166710-A1 Polycarbonate Containing Compounds and Methods Related Thereto ERCC5, ERCC1, PPOX KIF11 3822/4885
US-20070031499-A1 Readily shapeable xerogels having controllably delayed swelling properties SMARCA2, SMARCA4, SMARCE1 KIF11 1297/4885
US-20170107255-A1 APELIN POLYPEPTIDES APLNR, FABP3, AP3B1 KIF11 3108/4885
US-20170182173-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT PTGIS, PTGIR, PGF KIF11 966/4885
US-10669538-B2 Templated molecules and methods for using such molecules ABL1, DHFR, TYMS KIF11 2340/4885
US-20170119907-A1 Targeted Therapeutics ANXA3, ANXA5, ANXA6 KIF11 532/4885
US-10308774-B2 Polycarbonate containing compounds and methods related thereto ERCC5, ERCC1, PPOX KIF11 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.