SCHEMBL368863

SCHEMBL368863

COC(C)(C)CCOC(C)(C)CCN

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MCHR1 Q99705 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8165469 0.87 ALDH1A1 (0.32) ALDH1A1TSHRTDP1
SCHEMBL14616012 0.86 KIF11 (0.31)
SCHEMBL4974374 0.85
SCHEMBL19003665 0.84 ALDH1A1 (0.36) ALDH1A1TSHRTDP1MCHR1
SCHEMBL19404364 0.84 DNM1 (0.31) ALDH1A1TSHRTDP1
SCHEMBL3175803 0.83
Hydrochloric Acid SCHEMBL15270046 0.83
SCHEMBL22301042 0.83
SCHEMBL22857442 0.83
SCHEMBL17994099 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143038-A1 POLYOL-CONTAINING COMPOSITION, AND POLYURETHANE AND WATER-BASED POLYURETHANE MADE THEREFROM 旭化成株式会社 2024-07-04 WO disclosed
WO-2024044327-A1 DHNT MONOMERS AND POLYMER DYES WITH MODIFIED PHOTOPHYSICAL PROPERTIES BECKMAN COULTER, INC. (US) 2024-02-29 WO disclosed
WO-2023244517-A1 INTERLEUKIN-2 PRODRUGS MERCK SHARP & DOHME LLC (US) 2023-12-21 WO disclosed
US-11730826-B2 Amphiphilic nanoparticles for delivery of CRISPR based therapy MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-08-22 US disclosed
WO-2023116702-A1 PH-SENSITIVE MEMBRANE-BREAKING POLYPEPTIDE AND USE THEREOF 华南理工大学 2023-06-29 WO disclosed
US-20230130084-A1 MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-04-27 US disclosed
US-20220211868-A1 NANOPARTICLES COMPRISING NON-CLASSICAL MHC AND USES THEREOF UTI LIMITED PARTNERSHIP (CA) 2022-07-07 US disclosed
US-20220193210-A1 THERAPEUTICS FOR AUTOIMMUNE KIDNEY DISEASE: SYNTHETIC ANTIGENS DANMARKS TEKNISKE UNIVERSITET (DK) 2022-06-23 US disclosed
US-11338024-B2 Methods and compositions for sustained immunotherapy UTI LIMITED PARTNERSHIP (CA) 2022-05-24 US disclosed
US-20220125752-A1 LEVODOPA DERIVATIVE AND USE THEREOF UNIVERSITY OF TSUKUBA (JP) 2022-04-28 US disclosed
US-20120101037-A1 GLUCOSE-DEPENDENT INSULINOTROPIC PEPTIDE ANALOGS HOFFMANN-LA ROCHE INC. 2012-04-26 US disclosed
US-20120094955-A1 METHOD OF DISSOLVING AN OXIDIZED POLYSACCHARIDE IN AN AQUEOUS SOLUTION ACTAMAX SURGICAL MATERIALS LLC (US) 2012-04-19 US disclosed
EP-1962959-B1 NEUROPEPTIDE-2 RECEPTOR-AGONISTS HOFFMANN LA ROCHE (CH) 2012-03-14 EP disclosed
US-20110284458-A1 COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND BIGUANIDE-TYPE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC 2011-11-24 US disclosed
WO-2011113065-A2 PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2011-09-15 WO disclosed
US-20110142886-A1 PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2011-06-16 US disclosed
WO-2010070132-A1 THIOIC ACIDS AS BUILDING BLOCK FOR POLYTHIOESTERS DSM IP ASSETS B.V. (NL) 2010-06-24 WO disclosed
US-20100112026-A1 SURFACES, METHODS AND DEVICES EMPLOYING CELL ROLLING MASSACHUSETTS INSTITUTE TO TECHNOLOGY (US) 2010-05-06 US disclosed
US-7276475-B2 Remodeling and glycoconjugation of peptides NEOSE TECHNOLOGIES, INC. (US) 2007-10-02 US disclosed
WO-2007065808-A2 NEUROPEPTIDE-2 RECEPTOR-AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2007-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110142886-A1 PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY PARN, PUF60, PARG ALDH1A1 4268/4885TSHR 3477/4885TDP1 271/4885
US-11730826-B2 Amphiphilic nanoparticles for delivery of CRISPR based therapy ABCB4, ABCB1, ZFR ALDH1A1 2916/4885TSHR 4119/4885TDP1 1596/4885
US-20120094955-A1 METHOD OF DISSOLVING AN OXIDIZED POLYSACCHARIDE IN AN AQUEOUS SOLUTION SI, OGFOD1, OSTC ALDH1A1 777/4885TSHR 3622/4885TDP1 2933/4885
US-20220193210-A1 THERAPEUTICS FOR AUTOIMMUNE KIDNEY DISEASE: SYNTHETIC ANTIGENS SSB, HAVCR2, CD47 ALDH1A1 3142/4885TSHR 460/4885TDP1 4872/4885
US-20120101037-A1 GLUCOSE-DEPENDENT INSULINOTROPIC PEPTIDE ANALOGS GIPR, GPR119, GLP1R ALDH1A1 4569/4885TSHR 102/4885TDP1 4725/4885
US-11338024-B2 Methods and compositions for sustained immunotherapy CD47, TFRC, ICOS ALDH1A1 3596/4885TSHR 1032/4885TDP1 3950/4885
US-20220125752-A1 LEVODOPA DERIVATIVE AND USE THEREOF PARK7, COMT, SNCA ALDH1A1 744/4885TSHR 2743/4885TDP1 1091/4885
US-20220211868-A1 NANOPARTICLES COMPRISING NON-CLASSICAL MHC AND USES THEREOF MICA, CD74, HLA-C ALDH1A1 1091/4885TSHR 3506/4885TDP1 4811/4885
US-20230130084-A1 MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY ALG1, CD44, CD47 ALDH1A1 511/4885TSHR 4751/4885TDP1 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.