Bevenopran

Bevenopran

SCHEMBL1462219

COc1cc(CNCCC2CCOCC2)ccc1Oc1cnc(C(N)=O)cn1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Bevenopran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 known ✓ P35372 1/20 0.41
MAPK1 P28482 2/20 0.42
LMNA P02545 1/20 0.42
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
KDM4E B2RXH2 3/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SIRT6 Q8N6T7 1/20 0.38
MCHR1 Q99705 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14159395 0.92 MAPK1 (0.42) MAPK1LMNAKDM4EPOLBCYP3A4
SCHEMBL12836114 0.91 LMNA (0.42) MAPK1LMNAKDM4EPOLBCYP3A4
SCHEMBL3691965 0.90 OPRM1 (0.41) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3692183 0.89 OPRM1 (0.41) OPRM1OPRD1OPRK1MCHR1CTSD
SCHEMBL3888284 0.88 OPRM1 (0.46) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3695565 0.88 OPRM1 (0.46) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3690720 0.87 OPRM1 (0.41) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3690745 0.85 OPRM1 (0.44) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3691865 0.85 OPRM1 (0.44) MAPK1LMNAOPRM1OPRD1OPRK1
SCHEMBL3705019 0.85 OPRM1 (0.47) OPRM1OPRD1OPRK1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137697-A1 METHODS, SYSTEMS, AND COMPOSITIONS RELATED TO USE OF MU OPIOID RECEPTOR (MOR) ANTAGONISTS GLYCYX MOR INC. (US) 2025-06-26 WO claimed
US-20240209403-A1 METHODS OF PRODUCING MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2024-06-27 US claimed
US-11884949-B2 Methods of producing morphinan alkaloids and derivatives ANTHEIA, INC. (US) 2024-01-30 US claimed
US-20230407258-A1 TREATMENT OF DISC DEGENERATIVE DISEASE AND STIMULATION OF PROTEOGLYCAN SYNTHESIS BY FIBROBLAST CONDITIONED MEDIA AND FORMULATIONS THEREOF FIGENE, LLC 2023-12-21 US claimed
EP-4031167-A1 TREATMENT OF DISC DEGENERATIVE DISEASE AND STIMULATION OF PROTEOGLYCAN SYNTHESIS BY FIBROBLAST CONDITIONED MEDIA AND FORMULATIONS THEREOF Figene, LLC (US) 2022-07-27 EP claimed
US-20220125844-A1 OPIOID ANTAGONISTS FOR USE IN PATIENTS USING CHIMERIC ANTIGEN RECEPTOR T AND NATURAL KILLER (NK) CELL THERAPY THE JOHNS HOPKINS UNIVERSITY 2022-04-28 US claimed
EP-2208727-B1 Diaryl ethers as opioid receptor antagonist LILLY CO ELI (US) 2012-08-29 EP claimed
JP-4646628-B2 2011-03-09 JP claimed
EP-2208727-A1 Diaryl ethers as opioid receptor antagonist Eli Lilly & Company (US) 2010-07-21 EP claimed
US-7560463-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-07-14 US claimed
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY 2008-10-16 US claimed
US-7381719-B2 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY (US) 2008-06-03 US claimed
EP-1562595-B1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 2008-05-21 EP claimed
CN-1305852-C Diaryl ethers as opioid receptor antagonists LILLY CO ELI (US) 2007-03-21 CN claimed
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY 2006-09-28 US claimed
JP-2006511474-A 2006-04-06 JP claimed
CN-1681498-A Diaryl ethers as opioid receptor antagonist LILLY CO ELI (US) 2005-10-12 CN claimed
EP-1562595-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2005-08-17 EP claimed
WO-2004026305-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST ELI LILLY AND COMPANY (US) 2004-04-01 WO claimed
EP-4739375-A1 HIGHLY PORTABLE GAS DELIVERY SYSTEMS Minogue, Michael R. (US) 2026-05-13 EP disclosed
US-12611418-B2 Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2026-04-28 US disclosed
US-20260103736-A1 Methods Of Improving Production Of Morphinan Alkaloids And Derivatives ANTHEIA INC (US) 2026-04-16 US disclosed
EP-3946547-B1 DEVICES AND METHODS FOR DELIVERING PHARMACEUTICAL COMPOSITIONS PINOVA THERAPEUTICS INC (US) 2026-03-25 EP disclosed
EP-4704806-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS Cybin IRL Limited (IE) 2026-03-11 EP disclosed
EP-4673140-A1 METHODS OF TREATING DEPRESSIVE DISORDERS WITH A PSILOCYBIN ANALOG Cybin IRL Limited (IE) 2026-01-07 EP disclosed
US-20250367223-A1 METHODS FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS PATHFINDER LIMITED (GB) 2025-12-04 US disclosed
US-20250360148-A1 SOLID DISPERSIONS OF PSILOCYBIN CYBIN IRL LIMITED (IE) 2025-11-27 US disclosed
US-12454520-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2025-10-28 US disclosed
US-12447164-B2 Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2025-10-21 US disclosed
US-20250312275-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2025-10-09 US disclosed
US-12433904-B2 Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2025-10-07 US disclosed
EP-4594342-A2 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES Antheia, Inc. (US) 2025-08-06 EP disclosed
US-20250236589-A1 THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE CYBIN IRL LIMITED (IE) 2025-07-24 US disclosed
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-07-03 US disclosed
US-20250213527-A1 FORMULATIONS OF PSILOCYBIN ANALOGS AND METHODS OF USE CYBIN IRL LIMITED (IE) 2025-07-03 US disclosed
WO-2025137697-A1 METHODS, SYSTEMS, AND COMPOSITIONS RELATED TO USE OF MU OPIOID RECEPTOR (MOR) ANTAGONISTS GLYCYX MOR INC. (US) 2025-06-26 WO disclosed
WO-2025106940-A1 HIGHLY PORTABLE GAS DELIVERY SYSTEMS MINOGUE MICHAEL R (US) 2025-05-22 WO disclosed
US-20250152889-A1 HIGHLY PORTABLE GAS DELIVERY SYSTEMS MINOGUE, MICHAEL 2025-05-15 US disclosed
US-20250145566-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2025-05-08 US disclosed
US-20250137021-A1 METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS HERCULES CAPITAL, INC., AS AGENT 2025-05-01 US disclosed
EP-4536179-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS Nanexa AB (SE) 2025-04-16 EP disclosed
US-20250082607-A2 METHODS OF TREATING DISORDERS WITH A PSILOCYBIN ANALOG CYBIN IRL LIMITED (IE) 2025-03-13 US disclosed
US-20250058094-A1 DEVICES AND METHODS FOR DELIVERY OF PHARMACEUTICAL COMPOSITIONS PINOVA THERAPEUTICS INC. 2025-02-20 US disclosed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US disclosed
US-12194263-B2 Devices and methods for delivery of pharmaceutical compositions Pocket Naloxone Corp. (US) 2025-01-14 US disclosed
US-12180525-B2 Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids ANTHEIA, INC. (US) 2024-12-31 US disclosed
WO-2024256696-A1 NEW INJECTABLE PHARMACEUTICAL DEPOT COMPOSITIONS NANEXA AB (SE) 2024-12-19 WO disclosed
US-20240404619-A1 Machine Learning and Molecular Simulation Based Methods for Enhancing Binding and Activity Prediction THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-12-05 US disclosed
EP-4463440-A1 TRYPTAMINE COMPOSITIONS AND METHODS Cybin IRL Limited (IE) 2024-11-20 EP disclosed
WO-2024231331-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS CYBIN IRL LIMITED (IE) 2024-11-14 WO disclosed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 EP disclosed
US-12100485-B2 Machine learning and molecular simulation based methods for enhancing binding and activity prediction THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-09-24 US disclosed
US-12090276-B1 Highly portable gas delivery systems Minogue, Michael R. (US) 2024-09-17 US disclosed
EP-4426675-A1 FORMULATIONS OF PSILOCYBIN ANALOGS AND METHODS OF USE Cybin IRL Limited (IE) 2024-09-11 EP disclosed
CN-118632835-A Tryptamine compositions and methods 赛本爱尔兰有限公司 2024-09-10 CN disclosed
WO-2024180030-A1 METHODS OF TREATING DEPRESSIVE DISORDERS WITH A PSILOCYBIN ANALOG CYBIN IRL LIMITED (IE) 2024-09-06 WO disclosed
US-20240293367-A1 METHODS OF TREATING DISORDERS WITH A PSILOCYBIN ANALOG CYBIN IRL LIMITED (IE) 2024-09-05 US disclosed
US-20240261228-A1 NEW PROCESS NANEXA AB (SE) 2024-08-08 US disclosed
US-20240252521-A1 METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS PATHFINDER LIMITED (GB) 2024-08-01 US disclosed
US-20240209403-A1 METHODS OF PRODUCING MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2024-06-27 US disclosed
CN-118234708-A Formulations of nudity alkali analogs and methods of use 赛本爱尔兰有限公司 2024-06-21 CN disclosed
WO-2024127018-A1 NEW INJECTABLE SUSPENSION OF COATED PARTICLES NANEXA AB (SE) 2024-06-20 WO disclosed
US-12006329-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-06-11 US disclosed
US-20240165103-A1 COMPOSITIONS AND METHODS FOR OPIOID ANTAGONIST DELIVERY PURDUE PHARMA LP (US) 2024-05-23 US disclosed
CN-112204402-B Methods for enhancing binding and activity prediction based on machine learning and molecular modeling 斯坦福大学托管董事会 2024-05-03 CN disclosed
EP-4351528-A1 NEW PROCESS Nanexa AB (SE) 2024-04-17 EP disclosed
WO-2024073755-A2 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES ANTHEIA, INC. (US) 2024-04-04 WO disclosed
US-20240102061-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2024-03-28 US disclosed
US-11884949-B2 Methods of producing morphinan alkaloids and derivatives ANTHEIA, INC. (US) 2024-01-30 US disclosed
US-11865126-B2 Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2024-01-09 US disclosed
US-11865112-B2 Compositions and methods for opioid antagonist delivery PURDUE PHARMA L.P. (US) 2024-01-09 US disclosed
US-11857547-B2 Compositions and methods for opioid antagonist delivery PURDUE PHARMA L.P. (US) 2024-01-02 US disclosed
WO-2023247665-A1 SOLID DISPERSIONS OF PSILOCYBIN CYBIN IRL LIMITED (IE) 2023-12-28 WO disclosed
US-20230407258-A1 TREATMENT OF DISC DEGENERATIVE DISEASE AND STIMULATION OF PROTEOGLYCAN SYNTHESIS BY FIBROBLAST CONDITIONED MEDIA AND FORMULATIONS THEREOF FIGENE, LLC 2023-12-21 US disclosed
WO-2023237897-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2023-12-14 WO disclosed
CN-116964190-A Method for increasing yields of morphinan alkaloids and derivatives 安思雅公司 2023-10-27 CN disclosed
US-20230330117-A1 METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS PATHFINDER LIMITED (GB) 2023-10-19 US disclosed
EP-4247937-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES Antheia, Inc. (US) 2023-09-27 EP disclosed
US-20230270741-A1 COMPOSITIONS AND METHODS FOR OPIOID ANTAGONIST DELIVERY PURDUE PHARMA LP (US) 2023-08-31 US disclosed
US-11738035-B2 Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2023-08-29 US disclosed
US-20230265153-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD (GB) 2023-08-24 US disclosed
US-11732239-B2 Treatment of disc degenerative disease and stimulation of proteoglycan synthesis by fibroblast conditioned media and formulations thereof FIGENE, LLC (US) 2023-08-22 US disclosed
WO-2023135237-A1 TRYPTAMINE COMPOSITIONS AND METHODS CYBIN IRL LIMITED (IE) 2023-07-20 WO disclosed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 WO disclosed
WO-2022109194-A9 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES ANTHEIA, INC. (US) 2023-06-08 WO disclosed
US-20230157968-A1 INJECTABLE OIL-BASED PHARMACEUTICAL COMPOSITION NANEXA AB (SE) 2023-05-25 US disclosed
WO-2023078604-A1 FORMULATIONS OF PSILOCYBIN ANALOGS AND METHODS OF USE CYBIN IRL LIMITED (IE) 2023-05-11 WO disclosed
CN-116075295-A Novel injectable oil-based pharmaceutical compositions 南爱克萨股份公司 2023-05-05 CN disclosed
US-20230126298-A1 DEUYERATED TRYPTAMINE DERIVATIVE FORMULATIONS AND METHODS OF USE CYBIN IRL LIMITED (IE) 2023-04-27 US disclosed
US-20230124137-A1 METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS PATHFINDER LIMITED (GB) 2023-04-20 US disclosed
US-11623932-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-04-11 US disclosed
US-20230104286-A1 METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS HERCULES CAPITAL, INC., AS AGENT 2023-04-06 US disclosed
EP-4135672-A1 INJECTABLE OIL-BASED PHARMACEUTICAL COMPOSITION Nanexa AB (SE) 2023-02-22 EP disclosed
US-11564935-B2 Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin COMPASS PATHFINDER LIMITED (GB) 2023-01-31 US disclosed
US-20230020272-A1 NEW PROCESS FOR THE MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2023-01-19 US disclosed
US-20230009472-A1 NEW COMPOSITION NANEXA AB (SE) 2023-01-12 US disclosed
US-11548928-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2023-01-10 US disclosed
US-20230000883-A1 METHODS FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN HERCULES CAPITAL, INC. 2023-01-05 US disclosed
WO-2022258984-A1 NEW PROCESS NANEXA AB (SE) 2022-12-15 WO disclosed
US-11518796-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2022-12-06 US disclosed
EP-4069198-A1 NEW PROCESS FOR THE MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS Nanexa AB (SE) 2022-10-12 EP disclosed
EP-4069190-A1 NEW COMPOSITION Nanexa AB (SE) 2022-10-12 EP disclosed
US-20220307132-A1 APPARATUS NANEXA AB (SE) 2022-09-29 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
CN-115087665-A Engineered platelets for targeted delivery of therapeutic agents JPV01有限公司 2022-09-20 CN disclosed
US-11427827-B2 Engineered benzylisoquinoline alkaloid epimerases and methods of producing benzylisoquinoline alkaloids ANTHEIA, INC. (US) 2022-08-30 US disclosed
US-20220251165-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-08-11 US disclosed
EP-4031167-A1 TREATMENT OF DISC DEGENERATIVE DISEASE AND STIMULATION OF PROTEOGLYCAN SYNTHESIS BY FIBROBLAST CONDITIONED MEDIA AND FORMULATIONS THEREOF Figene, LLC (US) 2022-07-27 EP disclosed
US-11396668-B2 Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids ANTHEIA, INC. (US) 2022-07-26 US disclosed
EP-4026898-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-07-13 EP disclosed
CN-114746078-A New composition 南爱克萨股份公司 2022-07-12 CN disclosed
WO-2022109194-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES ANTHEIA, INC. (US) 2022-05-27 WO disclosed
US-20220162656-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2022-05-26 US disclosed
EP-3990679-A1 APPARATUS FOR FORMING A PLURALITY OF COATED PARTICLES, METHOD FOR FORMING A PLURALITY OF COATED PARTICLES, COATED PARTICLES Nanexa AB (SE) 2022-05-04 EP disclosed
US-20220125844-A1 OPIOID ANTAGONISTS FOR USE IN PATIENTS USING CHIMERIC ANTIGEN RECEPTOR T AND NATURAL KILLER (NK) CELL THERAPY THE JOHNS HOPKINS UNIVERSITY 2022-04-28 US disclosed
US-20220088041-A1 METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS PATHFINDER LIMITED (GB) 2022-03-24 US disclosed
US-20220071991-A1 EXTENDED RELEASE COMPOSITIONS OF OPIOID ANTAGONISTS AND PHOSPHODIESTERASE 5 INHIBITORS PARDON MY SCOTCH LLC (US) 2022-03-10 US disclosed
US-20220062602-A1 DEVICES AND METHODS FOR DELIVERY OF PHARMACEUTICAL COMPOSITIONS PINOVA THERAPEUTICS INC. 2022-03-03 US disclosed
EP-3955919-A1 METHODS FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN COMPASS Pathfinder Limited (GB) 2022-02-23 EP disclosed
US-20220041684-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-02-10 US disclosed
EP-3946547-A1 DEVICES AND METHODS FOR DELIVERING PHARMACEUTICAL COMPOSITIONS Pocket Naloxone Corp. (US) 2022-02-09 EP disclosed
EP-3947633-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES Antheia, Inc. (US) 2022-02-09 EP disclosed
EP-3947434-A2 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-02-09 EP disclosed
CN-114026265-A Apparatus for forming a plurality of coated particles, method for forming a plurality of coated particles, coated particles 南爱克萨股份公司 2022-02-08 CN disclosed
CN-113993522-A Method for treating anxiety disorders, headache disorders and eating disorders with siloxibin 指南针探路者有限公司 2022-01-28 CN disclosed
CN-104958298-A Use of an opioid receptor antagonist for the treatment or prevention of gastrointestinal tract disorders ADOLOR CORP 2015-10-07 CN disclosed
CN-102695508-A Use of opioid receptor antagonists for gastrointestinal disorders ADOLOR CORP 2012-09-26 CN disclosed
EP-2208727-B1 Diaryl ethers as opioid receptor antagonist LILLY CO ELI (US) 2012-08-29 EP disclosed
EP-2477627-A1 USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS Adolor Corporation (US) 2012-07-25 EP disclosed
EP-2477627-A1 USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS Adolor Corporation (US) 2012-07-25 EP disclosed
WO-2011035142-A1 USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 WO disclosed
WO-2011035142-A1 USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 WO disclosed
WO-2011035142-A1 USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 WO disclosed
US-20110071163-A1 USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 US disclosed
US-20110071163-A1 USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 US disclosed
US-20110071163-A1 USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 US disclosed
US-20110071163-A1 USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS ADOLOR CORPORATION (US) 2011-03-24 US disclosed
EP-2208727-A1 Diaryl ethers as opioid receptor antagonist Eli Lilly & Company (US) 2010-07-21 EP disclosed
EP-2208727-A1 Diaryl ethers as opioid receptor antagonist Eli Lilly & Company (US) 2010-07-21 EP disclosed
US-7560463-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-07-14 US disclosed
US-7560463-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-07-14 US disclosed
US-7560463-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-07-14 US disclosed
US-7560463-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-07-14 US disclosed
US-7531557-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-05-12 US disclosed
US-7531557-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-05-12 US disclosed
US-7531557-B2 Diaryl ethers as opioid receptor antagonists ELI LILLY AND COMPANY (US) 2009-05-12 US disclosed
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS BLANCO-PILLADO MARIA-JESUS 2008-10-30 US disclosed
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS BLANCO-PILLADO MARIA-JESUS 2008-10-30 US disclosed
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS BLANCO-PILLADO MARIA-JESUS 2008-10-30 US disclosed
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY 2008-10-16 US disclosed
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY 2008-10-16 US disclosed
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY 2008-10-16 US disclosed
US-7381719-B2 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY (US) 2008-06-03 US disclosed
US-7381719-B2 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY (US) 2008-06-03 US disclosed
US-7381719-B2 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY (US) 2008-06-03 US disclosed
EP-1562595-B1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 2008-05-21 EP disclosed
EP-1562595-B1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 2008-05-21 EP disclosed
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY 2006-09-28 US disclosed
EP-1562595-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2005-08-17 EP disclosed
WO-2004026305-A9 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST LILLY CO ELI (US) 2004-05-13 WO disclosed
WO-2004026305-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST ELI LILLY AND COMPANY (US) 2004-04-01 WO disclosed
WO-2004026305-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST ELI LILLY AND COMPANY (US) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082607-A2 METHODS OF TREATING DISORDERS WITH A PSILOCYBIN ANALOG HTR2C, HTR1B, HTR2A OPRM1 16/4885MAPK1 4726/4885LMNA 286/4885
US-20250236589-A1 THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE PNMT, HTR2C, HTR2A OPRM1 40/4885MAPK1 4459/4885LMNA 2310/4885
US-12006329-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 OPRM1 4693/4885MAPK1 3746/4885LMNA 2563/4885
US-20250213527-A1 FORMULATIONS OF PSILOCYBIN ANALOGS AND METHODS OF USE HTR2C, HTR2A, HTR2B OPRM1 21/4885MAPK1 4757/4885LMNA 2239/4885
US-20260103736-A1 Methods Of Improving Production Of Morphinan Alkaloids And Derivatives OPRK1, OPRM1, OPRD1 OPRM1 2/4885MAPK1 4009/4885LMNA 3778/4885
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS OPRM1, OPRD1, OPRL1 OPRM1 1/4885MAPK1 2452/4885LMNA 4007/4885
US-20250360148-A1 SOLID DISPERSIONS OF PSILOCYBIN HTR2B, HTR2A, HTR2C OPRM1 181/4885MAPK1 4622/4885LMNA 3478/4885
US-12454520-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 OPRM1 4693/4885MAPK1 3746/4885LMNA 2563/4885
US-12611418-B2 Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin HTR1D, HTR1B, HTR2B OPRM1 114/4885MAPK1 3396/4885LMNA 534/4885
US-11623932-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 OPRM1 4693/4885MAPK1 3746/4885LMNA 2563/4885
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 OPRM1 4693/4885MAPK1 3746/4885LMNA 2563/4885
US-20110071163-A1 USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS OPRM1, OPRK1, OPRL1 OPRM1 1/4885MAPK1 640/4885LMNA 4639/4885
US-20240293367-A1 METHODS OF TREATING DISORDERS WITH A PSILOCYBIN ANALOG HTR2C, HTR1B, HTR2A OPRM1 16/4885MAPK1 4726/4885LMNA 286/4885
US-20230126298-A1 DEUYERATED TRYPTAMINE DERIVATIVE FORMULATIONS AND METHODS OF USE TPH2, HTR2A, HTR2C OPRM1 197/4885MAPK1 4798/4885LMNA 1766/4885
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS OPRM1, OPRD1, OPRL1 OPRM1 1/4885MAPK1 2410/4885LMNA 3993/4885
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist OPRM1, OPRL1, OPRD1 OPRM1 1/4885MAPK1 2437/4885LMNA 3897/4885
US-20250145566-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE PNMT, HTR7, HTR2C OPRM1 31/4885MAPK1 2955/4885LMNA 2631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.