Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325651 | 0.91 | LMNA (0.47) | KDM4EMAPTMEN1KMT2ADRD4 | |
| SCHEMBL5325599 | 0.87 | KDM4E (0.38) | KDM4EMAPTMEN1KMT2AABCB1 | |
| SCHEMBL5321659 | 0.86 | ALOX15 (0.43) | KDM4EMAPTMEN1KMT2AABCB1 | |
| SCHEMBL5285665 | 0.85 | HSD17B10 (0.35) | KDM4EMAPTMEN1KMT2AABCB1 | |
| SCHEMBL14622410 | 0.85 | MAPT (0.43) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5323186 | 0.84 | MAPT (0.51) | KDM4EMAPTMEN1KMT2AHTR1A | |
| SCHEMBL5322162 | 0.83 | SLC6A7 (0.41) | KDM4EMAPTMEN1KMT2AHTR1A | |
| SCHEMBL14622908 | 0.83 | DRD2 (0.38) | HTR1ADRD2DRD3 | |
| SCHEMBL5321578 | 0.80 | PTGS2 (0.37) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL5323252 | 0.80 | PTGS2 (0.35) | MAPTLMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |