Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.51 |
| ▸ | MMP13 | P45452 | 12/20 | 0.51 |
| ▸ | MMP3 | P08254 | 8/20 | 0.51 |
| ▸ | MMP1 | P03956 | 7/20 | 0.51 |
| ▸ | MMP9 | P14780 | 6/20 | 0.51 |
| ▸ | MMP8 | P22894 | 3/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636108 | 0.88 | MMP13 (0.52) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL14636309 | 0.84 | SLC1A3 (0.41) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7075250 | 0.74 | MMP13 (0.59) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL2161549 | 0.71 | MMP9 (0.92) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL2161452 | 0.71 | MMP9 (0.92) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL5839717 | 0.71 | MMP9 (0.92) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4619973 | 0.70 | MMP2 (0.68) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4618694 | 0.70 | MMP2 (0.68) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4621342 | 0.70 | MMP2 (0.68) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4619626 | 0.70 | MMP2 (0.66) | MMP2MMP13MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220227792-A1 | CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE AGENTS FOR BORON NEUTRON CAPTURE THERAPY | LOYOLA UNIVERSITY OF CHICAGO | 2022-07-21 | — | — | US | disclosed |
| WO-2020252439-A1 | CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE AGENTS FOR BORON NEUTRON CAPTURE THERAPY | LOYOLA UNIVERSITY OF CHICAGO (US) | 2020-12-17 | — | — | WO | disclosed |
| WO-2013010573-A1 | COMPOUNDS WITH MATRIX-METALLOPROTEINASE INHIBITORY ACTIVITY | UNIVERSITAET MUENSTER (DE) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227792-A1 | CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE AGENTS FOR BORON NEUTRON CAPTURE THERAPY | MMP9, MMP26, MMP25 | MMP2 9/4885MMP13 11/4885MMP3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.