Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 12/20 | 0.41 |
| ▸ | MMP2 | P08253 | 11/20 | 0.41 |
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 8/20 | 0.41 |
| ▸ | MMP8 | P22894 | 7/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636108 | 0.87 | MMP13 (0.52) | MMP13MMP2MMP1MMP9MMP8 | |
| SCHEMBL14636268 | 0.84 | MMP2 (0.51) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL7305749 | 0.72 | MMP13 (0.71) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL7344506 | 0.71 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL7344510 | 0.71 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL7301899 | 0.68 | MMP1 (0.49) | MMP13MMP2MMP1MMP9MMP8 | |
| SCHEMBL7312224 | 0.65 | ADAM17 (0.48) | MMP13MMP2MMP1MMP3HSD17B10 | |
| SCHEMBL7892155 | 0.64 | ALDH1A1 (0.66) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL7087648 | 0.64 | MMP9 (0.64) | SLC1A3SLC1A2SLC1A1MMP13MMP2 | |
| SCHEMBL5093836 | 0.64 | MMP9 (0.64) | SLC1A3SLC1A2SLC1A1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010573-A1 | COMPOUNDS WITH MATRIX-METALLOPROTEINASE INHIBITORY ACTIVITY | UNIVERSITAET MUENSTER (DE) | 2013-01-24 | — | — | WO | disclosed |