Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.52 |
| ▸ | MMP1 | P03956 | 12/20 | 0.52 |
| ▸ | MMP9 | P14780 | 14/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636268 | 0.88 | MMP2 (0.51) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL14636309 | 0.87 | SLC1A3 (0.41) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL7376000 | 0.72 | MMP9 (0.74) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL7375998 | 0.72 | MMP9 (0.74) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL7417565 | 0.72 | MMP9 (0.64) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL5226437 | 0.71 | MMP13 (0.58) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL1565606 | 0.71 | MMP13 (0.58) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6928607 | 0.69 | MMP1 (1.00) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL7416701 | 0.69 | ALDH1A1 (0.58) | MMP13MMP1MMP9ADAM17MMP2 | |
| SCHEMBL6934594 | 0.69 | MMP1 (0.73) | MMP13MMP1MMP9ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010573-A1 | COMPOUNDS WITH MATRIX-METALLOPROTEINASE INHIBITORY ACTIVITY | UNIVERSITAET MUENSTER (DE) | 2013-01-24 | — | — | WO | disclosed |