Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | PHGDH | O43175 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070807 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL132620 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL1936559 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL5819282 | 0.76 | HSD17B10 (0.52) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL7670418 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL9470190 | 0.76 | ALDH1A1 (0.94) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL8956322 | 0.76 | ALDH1A1 (0.94) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL11243942 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| Fluoride SCHEMBL28728322 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TAS2R38HSD17B10CYP3A4GAA | |
| SCHEMBL1466506 | 0.75 | MDM2 (0.54) | ALDH1A1GAAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700655-B2 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-04-20 | — | — | US | claimed |
| US-7494815-B2 | Method and apparatus for analyzing compounds with amino group | AJINOMOTO CO., INC. (JP) | 2009-02-24 | — | — | US | claimed |
| US-20080311074-A1 | Inhibitors against activation of NF-kappaB | INSTITUTE OF MEDICAL MOLECULAR DESIGN INC. (JP) | 2008-12-18 | — | — | US | claimed |
| US-20080234233-A1 | MEDICAMENT FOR TREATMENT OF NEURODEGENERATIVE DISEASES | INSTITUTE OF MEDICINAL MOLECULAR DESIGN INC. (JP) | 2008-09-25 | — | — | US | claimed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-04-17 | — | — | US | claimed |
| US-20070269899-A1 | METHOD AND APPARATUS FOR ANALYZING COMPOUNDS WITH AMINO GROUP | AJINOMOTO CO. INC. (JP) | 2007-11-22 | — | — | US | claimed |
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | claimed |
| US-20070185110-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | claimed |
| EP-1758849-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | Novartis AG (CH) | 2007-03-07 | — | — | EP | claimed |
| EP-0752986-A1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1997-01-15 | — | — | EP | claimed |
| EP-0749964-A1 | N-Heterocyclyl biphenyl sulfonamides | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | claimed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | claimed |
| EP-0687473-A1 | OPTICAL ISOMERIZATION INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-12-20 | — | — | EP | claimed |
| EP-0682016-A1 | Pyridine derivatives | ZENECA LIMITED (GB) | 1995-11-15 | — | — | EP | claimed |
| WO-1995026957-A1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1995-10-12 | — | — | WO | claimed |
| US-5270213-A | Protein sequencing | PORTON INSTRUMENTS, INC. (US) | 1993-12-14 | — | — | US | claimed |
| EP-0360079-A1 | Tricyclic compounds, processes for their preparation and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | claimed |
| US-4865994-A | REACTING 2-ANILINO-S-THIAZOLINONE MODIFIED AMINO ACID WITH AMINO COMPOUND LABELED WITH RADIOACTIVE ISOTOPE | SEIKO INSTRUMENTS & ELECTRONICS LTD. (JP) | 1989-09-12 | — | — | US | claimed |
| EP-0005507-A1 | Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311074-A1 | Inhibitors against activation of NF-kappaB | NFKBIA, IKBKB, RELA | ALDH1A1 2096/4885TAS2R38 4858/4885HSD17B10 2440/4885 |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | MB, ACHE, ADORA2B | ALDH1A1 90/4885TAS2R38 4446/4885HSD17B10 2142/4885 |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | NAT1, EPX, HRH2 | ALDH1A1 364/4885TAS2R38 4295/4885HSD17B10 761/4885 |
| US-20080234233-A1 | MEDICAMENT FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAPT, TFEB, MAOA | ALDH1A1 425/4885TAS2R38 3896/4885HSD17B10 1152/4885 |
| US-20070185110-A1 | Antiallergic agents | NAT1, EPX, AHR | ALDH1A1 340/4885TAS2R38 4203/4885HSD17B10 855/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | ALDH1A1 362/4885TAS2R38 4280/4885HSD17B10 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.