Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.61 |
| ▸ | PRKCI | P41743 | 4/20 | 0.59 |
| ▸ | AXL | P30530 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.52 |
| ▸ | IKBKB | O14920 | 3/20 | 0.52 |
| ▸ | CHUK | O15111 | 3/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605623 | 1.00 | NUDT1 (0.61) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL2240671 | 0.77 | AURKB (0.71) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL4791546 | 0.76 | NUDT1 (0.71) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL12127219 | 0.76 | NUDT1 (0.62) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL858771 | 0.74 | PRKCI (0.59) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL3339974 | 0.74 | PRKCI (0.59) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL99690 | 0.74 | PRKCI (1.00) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL91443 | 0.74 | PRKCI (0.59) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL21062776 | 0.74 | PRKCI (0.59) | NUDT1PRKCIAXLAURKBIKBKB | |
| SCHEMBL1176829 | 0.74 | PRKCI (0.59) | NUDT1PRKCIAXLAURKBIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554170-A | Preparation method of 4-fluoro-7-azaindole | 上海大学 | 2023-08-08 | — | — | CN | claimed |
| US-20250361233-A1 | Compounds For Activating Serotonin Receptor | Psylo Pty Ltd (AU) | 2025-11-27 | — | — | US | disclosed |
| US-12415804-B2 | Compounds for activating a serotonin receptor | Psylo Pty Ltd (AU) | 2025-09-16 | — | — | US | disclosed |
| US-20250206739-A1 | Compounds | Psylo Pty Ltd (AU) | 2025-06-26 | — | — | US | disclosed |
| US-20250163044-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2025-05-22 | — | — | US | disclosed |
| US-20250041319-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC | 2025-02-06 | — | — | US | disclosed |
| EP-4452979-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2024-10-30 | — | — | EP | disclosed |
| US-20240327400-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-03 | — | — | US | disclosed |
| US-12029744-B2 | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | RIBOSCIENCE LLC (US) | 2024-07-09 | — | — | US | disclosed |
| CN-115215861-B | Aromatic heterocycle substituted alkyne compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-1756108-A2 | AZAINDOLES USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES | Vertex Pharmaceuticals Incorporated (US) | 2007-02-28 | — | — | EP | disclosed |
| US-20060058304-A1 | Azaindole kinase inhibitors | BHIDE RAJEEV S | 2006-03-16 | — | — | US | disclosed |
| US-20060003968-A1 | Azaindoles useful as inhibitors of rock and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2006-01-05 | — | — | US | disclosed |
| US-6969717-B2 | Azaindole kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-29 | — | — | US | disclosed |
| WO-2005103050-A2 | AZAINDOLES USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-11-03 | — | — | WO | disclosed |
| CN-1681818-A | Azaindole kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2005-10-12 | — | — | CN | disclosed |
| US-20050137201-A1 | Compositions useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2005-06-23 | — | — | US | disclosed |
| EP-1539763-A1 | AZAINDOLE KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040063707-A1 | Azaindole kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-01 | — | — | US | disclosed |
| WO-2004009601-A1 | AZAINDOLE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206739-A1 | Compounds | NLN, SLC18A2, PYGB | NUDT1 1111/4885PRKCI 3462/4885AXL 4487/4885 |
| US-12415804-B2 | Compounds for activating a serotonin receptor | HTR2C, HTR6, HTR2A | NUDT1 1560/4885PRKCI 2697/4885AXL 2597/4885 |
| US-20250361233-A1 | Compounds For Activating Serotonin Receptor | HTR2C, HTR2A, HTR6 | NUDT1 1712/4885PRKCI 2973/4885AXL 2342/4885 |
| US-20060003968-A1 | Azaindoles useful as inhibitors of rock and other protein kinases | ROCK2, ROCK1, TNK2 | NUDT1 2039/4885PRKCI 37/4885AXL 2432/4885 |
| US-20250041319-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | ENPP1, ENPP3, SMPD1 | NUDT1 110/4885PRKCI 839/4885AXL 4496/4885 |
| US-20040063707-A1 | Azaindole kinase inhibitors | FGFR1, FGFR2, FLT1 | NUDT1 2289/4885PRKCI 757/4885AXL 103/4885 |
| US-12029744-B2 | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | ENPP1, ENPP3, SMPD1 | NUDT1 103/4885PRKCI 924/4885AXL 4484/4885 |
| US-20250163044-A1 | COMPOUNDS | NLN, SLC18A2, PYGB | NUDT1 1111/4885PRKCI 3462/4885AXL 4487/4885 |
| US-20060058304-A1 | Azaindole kinase inhibitors | FGFR1, FGFR2, FLT1 | NUDT1 2092/4885PRKCI 754/4885AXL 82/4885 |
| US-20050137201-A1 | Compositions useful as inhibitors of protein kinases | MAP3K20, PACSIN2, MAP3K6 | NUDT1 2299/4885PRKCI 24/4885AXL 1103/4885 |
| US-20240327400-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, PDK1 | NUDT1 2743/4885PRKCI 1258/4885AXL 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.