SCHEMBL14698490

SCHEMBL14698490

N#Cc1cc(Cl)c2[nH]c(=O)oc(=O)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.47
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
F2 P00734 1/20 0.34
CFD P00746 1/20 0.34
KMO O15229 1/20 0.34
GRM5 P41594 1/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
GPR35 Q9HC97 2/20 0.32
GRIN2D O15399 2/20 0.31
GRIN3B O60391 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
GRIN2B Q13224 2/20 0.31
GRIN2C Q14957 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2904782 0.81 NOS3 (0.40) FASNNOS3NOS1NOS2F2
SCHEMBL30804569 0.78 HSD17B10 (0.43) NOS3NOS1NOS2F2CFD
SCHEMBL2061473 0.78 HSD17B10 (0.43) NOS3NOS1NOS2F2CFD
SCHEMBL14698412 0.78 CTDSP1 (0.37) NOS3NOS1NOS2F2CFD
SCHEMBL14698260 0.76 MAOA (0.39) NOS3NOS1NOS2F2CFD
SCHEMBL14698522 0.72 MAOA (0.40) F2CFDKMOGRM5PIM1
SCHEMBL6359370 0.71 NOS3 (0.61) FASNNOS3NOS1NOS2F2
SCHEMBL1904323 0.68 F2 (0.52) F2CFDKDM4EALDH1A1HSD17B10
SCHEMBL24876280 0.68 F2 (0.36) NOS3NOS1NOS2F2CFD
SCHEMBL30087001 0.66 LMNA (0.38) NOS3NOS1NOS2F2CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556141-B2 Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof BASF SE (DE) 2017-01-31 US disclosed
US-9282741-B2 Aniline type compounds BASF SE (DE) 2016-03-15 US disclosed
EP-2782910-B1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2016-02-03 EP disclosed
EP-2742037-B1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2015-10-14 EP disclosed
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150250174-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS BASF SE (DE) 2015-09-10 US disclosed
US-20150250172-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS BASF SE (DE) 2015-09-10 US disclosed
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
EP-2903438-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-08-12 EP disclosed
WO-2014053407-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053402-A1 METHOD FOR CONTROLLING NON-CROP PESTS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053396-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053406-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053401-A2 METHOD OF IMPROVING PLANT HEALTH BASF SE (DE) 2014-04-10 WO disclosed
WO-2013076092-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2013-05-30 WO disclosed
WO-2013024008-A1 ANILINE TYPE COMPOUNDS BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024007-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBONYLCHLORIDE COMPOUNDS BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024010-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024009-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250174-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS NAT1, TST, NIT2 FASN 869/4885NOS3 118/4885NOS1 92/4885
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS AADAC, ARSA, SIRT7 FASN 2341/4885NOS3 632/4885NOS1 1139/4885
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS MCU, AGK, MLYCD FASN 860/4885NOS3 2217/4885NOS1 3389/4885
US-20150250172-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS HRH3, DDT, ANTXR2 FASN 1315/4885NOS3 1879/4885NOS1 1804/4885
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS RYR2, RYR1, CRY1 FASN 3984/4885NOS3 3110/4885NOS1 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.