Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3733730 | 0.84 | VDR (0.47) | VDRMMP2ALDH1A1KDM4EHPGD | |
| SCHEMBL5185491 | 0.83 | VDR (0.54) | VDRMMP2ALDH1A1KDM4EHPGD | |
| SCHEMBL3739465 | 0.83 | VDR (0.51) | VDRMMP2ALDH1A1KDM4EHPGD | |
| SCHEMBL28290954 | 0.80 | PKM (0.53) | VDRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL2531424 | 0.80 | VDR (0.51) | VDRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL631561 | 0.79 | KMT2A (0.50) | VDRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL15006565 | 0.78 | VDR (0.46) | VDRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL8217662 | 0.77 | CYP2D6 (0.52) | VDRALDH1A1KDM4EHPGDPKM | |
| Water SCHEMBL16927693 | 0.77 | KMT2A (0.49) | VDRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL64214 | 0.76 | PARL (0.68) | VDRMMP2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | HTR3C, NPEPPS, RAP2C | VDR 1354/4885MMP2 2735/4885ALDH1A1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.