Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728568 | 0.77 | USP2 (0.33) | USP2 | |
| SCHEMBL14728601 | 0.73 | PIK3CB (0.34) | — | |
| SCHEMBL15843945 | 0.71 | GSK3B (0.50) | — | |
| SCHEMBL14728428 | 0.70 | ROCK2 (0.30) | — | |
| SCHEMBL14728548 | 0.67 | PIK3CB (0.32) | — | |
| SCHEMBL14728249 | 0.65 | CCR2 (0.32) | — | |
| SCHEMBL15762046 | 0.61 | MAOA (0.37) | — | |
| SCHEMBL13818593 | 0.60 | GABRA1 (0.32) | — | |
| SCHEMBL13199992 | 0.58 | KDM4E (0.45) | — | |
| SCHEMBL13446868 | 0.56 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028263-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |