SCHEMBL14734847

SCHEMBL14734847

Cc1cc(C)c(S(C)(=O)=O)cc1C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC9A1 P19634 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531009 0.81 SLC9A1 (0.85) SLC9A1
SCHEMBL34471843 0.79 NNMT (0.48) SLC9A1
SCHEMBL8580625 0.78 SLC9A1 (0.45) SLC9A1
SCHEMBL4638397 0.77 NNMT (0.47) —
SCHEMBL7083041 0.76 NNMT (0.50) SLC9A1
SCHEMBL31401329 0.76 ALDH1A1 (0.51) SLC9A1
SCHEMBL10177915 0.76 L3MBTL1 (0.56) SLC9A1
SCHEMBL17689083 0.76 ALDH1A1 (0.51) SLC9A1
SCHEMBL11821417 0.74 L3MBTL1 (0.46) SLC9A1
SCHEMBL15478488 0.74 RAPGEF4 (0.52) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019055590-A1 BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF AMGEN INC. (US) 2019-03-21 — — WO disclosed
US-20190077793-A1 BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF AMGEN INC. 2019-03-14 — — US disclosed
EP-2563787-B1 AZAINDAZOLE AMIDE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS BOEHRINGER INGELHEIM INT (DE) 2014-11-26 — — EP disclosed
US-8871786-B2 Azaindazole amide compounds as CCR1 receptor antagonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-10-28 — — US disclosed
US-20130203803-A1 Azaindazole Amide Compounds As CCR1 Receptor Antagonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-08-08 — — US disclosed
EP-2563787-A1 AZAINDAZOLE AMIDE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS Boehringer Ingelheim International GmbH (DE) 2013-03-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077793-A1 BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF TNNI3, TNNT2, TNNC1 SLC9A1 586/4885
US-20130203803-A1 Azaindazole Amide Compounds As CCR1 Receptor Antagonists CCR1, CCR3, CCR4 SLC9A1 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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