Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743685 | 0.88 | KCNMA1 (0.55) | MAPK1ALDH1A1KDM4ELMNAKCNMA1 | |
| SCHEMBL14743107 | 0.88 | LMNA (0.49) | MAPK1ALDH1A1KDM4ELMNAKCNMA1 | |
| SCHEMBL14742913 | 0.86 | RAB9A (0.49) | MAPK1ALDH1A1KDM4EKCNMA1HPGD | |
| SCHEMBL14743578 | 0.83 | RORC (0.44) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14744025 | 0.80 | NOTUM (0.51) | ALDH1A1KDM4ELMNAHPGDMEN1 | |
| SCHEMBL14744022 | 0.80 | MAPT (0.39) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL14743289 | 0.79 | ALDH1A1 (0.49) | MAPK1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL14743986 | 0.79 | L3MBTL1 (0.42) | ALDH1A1KDM4ELMNAHPGDMEN1 | |
| SCHEMBL14744278 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL14743640 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4ELMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |