Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743294 | 0.90 | POLB (0.55) | MAPK8MAPK10POLBHTTNPC1 | |
| SCHEMBL14743578 | 0.89 | RORC (0.44) | NOD2POLBHTTALDH1A1RORC | |
| SCHEMBL14743690 | 0.88 | KDM4C (0.47) | MAPK8MAPK10NOD2HTTNPC1 | |
| SCHEMBL14743107 | 0.84 | LMNA (0.49) | MAPK10POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL14743545 | 0.83 | CHUK (0.46) | POLBHTTNPC1RAB9AALDH1A1 | |
| SCHEMBL14743078 | 0.81 | HTT (0.50) | MAPK8MAPK10POLBHTTNPC1 | |
| SCHEMBL14744260 | 0.80 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL14743310 | 0.78 | MEN1 (0.52) | POLBHTTNPC1RAB9AALDH1A1 | |
| SCHEMBL14743950 | 0.78 | PYGL (0.46) | MAPK10HTTRAB9AALDH1A1MEN1 | |
| SCHEMBL14744254 | 0.78 | POLB (0.49) | POLBHTTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |