Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198567 | 0.85 | MAPT (0.53) | L3MBTL1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL27671029 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL4249931 | 0.78 | GPR119 (0.47) | MAPTMEN1KMT2ANPSR1GAA | |
| SCHEMBL30718973 | 0.76 | L3MBTL1 (0.41) | L3MBTL1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL1712875 | 0.76 | DRD2 (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL22668889 | 0.74 | MAPT (0.54) | L3MBTL1MAPTMAPK1GAAKDM4E | |
| SCHEMBL28132995 | 0.73 | LMNA (0.42) | L3MBTL1MAPK1MEN1KMT2AGAA | |
| SCHEMBL7023211 | 0.71 | DRD2 (0.42) | MAPTKMT2AKDM4EDRD2DRD1 | |
| SCHEMBL2784883 | 0.71 | DRD2 (0.45) | MAPK1DRD2DRD1DRD4DRD5 | |
| SCHEMBL31239122 | 0.71 | DRD2 (0.42) | L3MBTL1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
| CN-1067057-C | Serotonin 5-HT1A and dopamin D2 receptor ligands | LUNDBECK & CO AS H (DK) | 2001-06-13 | — | — | CN | disclosed |
| CN-1154107-A | 5-hydroxytryptamine 5-HT1AAnd dopamine D2Receptor ligands | LUNDBECK & CO AS H (DK) | 1997-07-09 | — | — | CN | disclosed |