Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719046 | 0.77 | KMT2A (0.54) | DRD2MAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL14744211 | 0.76 | L3MBTL1 (0.67) | L3MBTL1DRD2MAPTALDH1A1MAPK1 | |
| SCHEMBL30718991 | 0.75 | ALDH1A1 (0.40) | L3MBTL1DRD2MAPTALDH1A1MAPK1 | |
| SCHEMBL30719034 | 0.74 | MAPT (0.47) | DRD2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30719032 | 0.74 | MAPT (0.47) | DRD2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL635407 | 0.74 | MAPT (0.49) | L3MBTL1DRD2MAPTALDH1A1KMT2A | |
| SCHEMBL29560409 | 0.74 | MAPT (0.49) | L3MBTL1DRD2MAPTALDH1A1KMT2A | |
| SCHEMBL3811084 | 0.74 | MAPT (0.43) | DRD2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30718969 | 0.74 | RAB9A (0.50) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7795700 | 0.73 | DRD2 (0.44) | DRD2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362141-A | Method for synthesizing axial chiral biaryl compound by palladium-catalyzed asymmetric hydrogenolysis | 中国科学院大连化学物理研究所 | 2024-01-09 | — | — | CN | disclosed |