SCHEMBL14762165

SCHEMBL14762165

CSc1cc2ccccc2cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 2/20 0.45
GLA P06280 1/20 0.45
TRPM4 Q8TD43 1/20 0.41
HPGD P15428 3/20 0.41
STAT3 P40763 1/20 0.41
CYP1A2 P05177 2/20 0.39
ALOX5 P09917 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
DAO P14920 3/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MITF O75030 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
MAPK1 P28482 1/20 0.37
NPC1 O15118 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23957896 0.83 CYP2A6 (0.42) GAAKDM4EALDH1A1HSD17B10GLA
SCHEMBL1955363 0.78 ALDH1A1 (0.42) GAAKDM4EALDH1A1HSD17B10GLA
SCHEMBL17086856 0.78 ASIC3 (0.47) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL14283780 0.77 ALOX15 (0.40) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL24403156 0.77 CYP1A2 (0.47) GAAKDM4EALDH1A1HPGDCYP1A2
SCHEMBL25890996 0.77 AR (0.44) KDM4EDAOMAPK1
SCHEMBL24924722 0.76 ALDH1A1 (0.37) GAAKDM4EALDH1A1HSD17B10GLA
SCHEMBL24924715 0.75 ALDH1A1 (0.49) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL14772212 0.75 TRPA1 (0.47) GAAKDM4EALDH1A1HPGDCYP1A2
SCHEMBL15780495 0.74 CYP2A6 (0.41) GAAKDM4EALDH1A1HSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230069804-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2023-03-02 US disclosed
US-20220048890-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2022-02-17 US disclosed
US-9911927-B2 Compounds having semiconducting properties and related compositions and devices FLEXTERRA, INC. (US) 2018-03-06 US disclosed
US-9911927-B2 Compounds having semiconducting properties and related compositions and devices FLEXTERRA, INC. (US) 2018-03-06 US disclosed
US-9911927-B2 Compounds having semiconducting properties and related compositions and devices FLEXTERRA, INC. (US) 2018-03-06 US disclosed
EP-2759543-B1 CHROMENE COMPOUND AND CURABLE COMPOSITION TOKUYAMA CORP (JP) 2017-07-19 EP disclosed
US-20160351832-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices USINVEST LLC 2016-12-01 US disclosed
US-20160351832-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices USINVEST LLC 2016-12-01 US disclosed
US-20160351832-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices USINVEST LLC 2016-12-01 US disclosed
US-8829202-B2 Condensed polycyclic aromatic compound, aromatic polymer, and method for synthesizing aromatic compound TEIJIN LIMITED (JP) 2014-09-09 US disclosed
US-8829202-B2 Condensed polycyclic aromatic compound, aromatic polymer, and method for synthesizing aromatic compound TEIJIN LIMITED (JP) 2014-09-09 US disclosed
EP-2755978-A1 COMPOUNDS HAVING SEMICONDUCTING PROPERTIES AND RELATED COMPOSITIONS AND DEVICES Polyera Corporation (US) 2014-07-23 EP disclosed
US-20140187792-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND TEIJIN LIMITED (JP) 2014-07-03 US disclosed
US-20140187792-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND TEIJIN LIMITED (JP) 2014-07-03 US disclosed
EP-2740735-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND Teijin Limited (JP) 2014-06-11 EP disclosed
WO-2013039842-A1 COMPOUNDS HAVING SEMICONDUCTING PROPERTIES AND RELATED COMPOSITIONS AND DEVICES POLYERA CORPORATION (US) 2013-03-21 WO disclosed
WO-2013039842-A1 COMPOUNDS HAVING SEMICONDUCTING PROPERTIES AND RELATED COMPOSITIONS AND DEVICES POLYERA CORPORATION (US) 2013-03-21 WO disclosed
US-20130062598-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION 2013-03-14 US disclosed
US-20130062598-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION 2013-03-14 US disclosed
US-20130062598-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices POLYERA CORPORATION 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048890-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING RBM17, SF3B1, SF3B5 GAA 2553/4885KDM4E 2544/4885ALDH1A1 3964/4885
US-20130062598-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices NES, KCNN2, MYB GAA 4207/4885KDM4E 3136/4885ALDH1A1 4080/4885
US-20140187792-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND PAH, C9, CCNB2 GAA 3677/4885KDM4E 2926/4885ALDH1A1 3601/4885
US-20160351832-A1 Compounds Having Semiconducting Properties and Related Compositions and Devices NES, KCNN2, MYB GAA 4207/4885KDM4E 3136/4885ALDH1A1 4080/4885
US-20230069804-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING RBM17, SF3B1, SF3B5 GAA 2553/4885KDM4E 2544/4885ALDH1A1 3964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.