Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 2/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234092 | 0.82 | HTT (0.57) | GAAALDH1A1KMT2AHTT | |
| SCHEMBL1376441 | 0.81 | GAA (0.51) | GAANPBWR1ALDH1A1KMT2AMCHR1 | |
| SCHEMBL14844549 | 0.78 | ALDH1A1 (0.56) | GAANPBWR1ALDH1A1KMT2AMCHR1 | |
| SCHEMBL4383612 | 0.76 | NPBWR1 (0.75) | GAANPBWR1ALDH1A1MCHR1HTT | |
| SCHEMBL14844531 | 0.74 | NPBWR1 (0.84) | NPBWR1ALDH1A1MCHR1HTT | |
| SCHEMBL18532426 | 0.74 | GAA (0.56) | GAANPBWR1ALDH1A1KMT2AMCHR1 | |
| SCHEMBL2361037 | 0.72 | HTT (0.54) | GAAALDH1A1KMT2AHTT | |
| SCHEMBL978628 | 0.71 | HTT (0.53) | GAANPBWR1ALDH1A1KMT2AHTT | |
| SCHEMBL27691970 | 0.71 | HTT (0.42) | GAANPBWR1ALDH1A1KMT2AHTT | |
| SCHEMBL2373869 | 0.69 | L3MBTL1 (0.44) | ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| EP-2763968-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050421-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | GAA 2637/4885NPBWR1 926/4885ALDH1A1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.