Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18699696 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL30994074 | 0.93 | RAB9A (0.57) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL14534068 | 0.92 | THRB (0.51) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL28013657 | 0.91 | THRB (0.56) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL19621716 | 0.88 | THRB (0.57) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL16661857 | 0.88 | MAPT (0.53) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL13777518 | 0.88 | THRB (0.48) | SMN1; SMN2NPC1MAPTRAB9ATHRB | |
| SCHEMBL9806249 | 0.88 | TSHR (0.59) | THRBALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL21556847 | 0.87 | MET (0.56) | SMN1; SMN2MAPTTHRBKMT2AAKR1B10 | |
| SCHEMBL18468552 | 0.87 | THRB (0.52) | SMN1; SMN2NPC1MAPTRAB9ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| US-11618823-B2 | High refractive index siloxane insert materials for embedded contact lenses | ALCON INC. (CH) | 2023-04-04 | — | — | US | claimed |
| EP-4121802-A1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| WO-2009015256-A2 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON, INC. (CH) | 2009-01-29 | — | — | WO | claimed |
| US-20080145405-A1 | Providing a clean device comprising a porous polymer core containing an ocular drug in it cavities and covered by a polymer shell permeable for passage of the drug(s); subjecting the device to a supercritical fluid to remove contaminants; sustained release; grafting or injection; vision defects | BAUSCH & LOMB INCORPORATED | 2008-06-19 | — | — | US | claimed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | claimed |
| US-20070218104-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATION | 2007-09-20 | — | — | US | claimed |
| US-20070218103-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATED | 2007-09-20 | — | — | US | claimed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | claimed |
| US-6353069-B1 | INTRAOCULAR LENSES THAT HAVE HIGH REFRACTIVE INDEXES, ARE FLEXIBLE AND TRANSPARENT, CAN BE INSERTED INTO EYE THROUGH RELATIVELY SMALL INCISION, RECOVER ORIGINAL SHAPE AFTER HAVING BEEN INSERTED, AND ARE FREE OF GLISTENINGS | ALCON MANUFACTURING, LTD. | 2002-03-05 | — | — | US | claimed |
| US-20020019492-A1 | Method of making high refractive index ophthalmic device materials | NOVARTIS AG (CH) | 2002-02-14 | — | — | US | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218104-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | IDUA, ACMSD, MLEC | SMN1; SMN2 433/4885NPC1 4011/4885MAPT 2778/4885 |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | SMN1; SMN2 4324/4885NPC1 4517/4885MAPT 2700/4885 |
| US-20070218103-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | IDUA, APEH, PAM | SMN1; SMN2 520/4885NPC1 4040/4885MAPT 2520/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | SMN1; SMN2 4546/4885NPC1 4720/4885MAPT 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.