SCHEMBL1490598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30074880	1.00	PTGES (0.49)	PTGESALDH1A1MEN1MAPTKMT2A
	SCHEMBL358629	0.88	MAPT (0.45)	PTGESALDH1A1MEN1MAPTKMT2A
	SCHEMBL31424455	0.84	PTGES (0.51)	PTGESMEN1MAPTKMT2AEGFR
	SCHEMBL30074833	0.82	PTGES (0.49)	PTGESMAPTEGFRLMNA
	SCHEMBL5767153	0.82	GPR35 (0.46)	ALDH1A1MEN1MAPTKMT2AKDM4E
	SCHEMBL26620010	0.82	PTGES (0.49)	PTGESALDH1A1MAPTCTSBEGFR
	SCHEMBL2249257	0.82	TSHR (0.45)	ALDH1A1MEN1MAPTKMT2AKDM4E
	SCHEMBL202476	0.82	PTGES (0.49)	PTGESMAPTEGFRLMNA
	SCHEMBL5766464	0.82	TDP1 (0.45)	ALDH1A1MEN1MAPTKMT2AKDM4E
	SCHEMBL3865236	0.78	CRHBP (0.53)	ALDH1A1MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.