Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404980 | 0.88 | TSHR (0.45) | TSHRMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL2250758 | 0.84 | TSHR (0.47) | TSHRMAPK1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL20494911 | 0.82 | TSHR (0.45) | TSHRMAPK1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL5766464 | 0.82 | TDP1 (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1490598 | 0.82 | PTGES (0.49) | MAPK1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL30074880 | 0.82 | PTGES (0.49) | MAPK1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL5767153 | 0.82 | GPR35 (0.46) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL3865236 | 0.78 | CRHBP (0.53) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5767008 | 0.78 | PIM1 (0.45) | MAPK1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL5766462 | 0.78 | ALDH1A1 (0.44) | TSHRMAPK1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12295970-B2 | Imidazoquinoline compounds and prodrugs thereof | UNIVERSITY OF KANSAS (US) | 2025-05-13 | — | — | US | disclosed |
| CN-114514228-B | Pyridinamide derivatives as agricultural fungicides | 环球化学股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4003976-B1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2024080788-A1 | NOVEL TRICYCLIC DERIVATIVE COMPOUND AND USES THEREOF | 한미약품 주식회사 | 2024-04-18 | — | — | WO | disclosed |
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2022-08-18 | — | — | US | disclosed |
| US-20220177472-A1 | IMIDAZOQUINOLINE COMPOUNDS AND PRODRUGS THEREOF | UNIVERSITY OF KANSAS (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220177472-A1 | IMIDAZOQUINOLINE COMPOUNDS AND PRODRUGS THEREOF | UNIVERSITY OF KANSAS (US) | 2022-06-09 | — | — | US | disclosed |
| EP-4003976-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | Globachem NV (BE) | 2022-06-01 | — | — | EP | disclosed |
| CN-114514228-A | Pyridinamide derivatives as agricultural fungicides | 环球化学股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | CORNELL UNIVERSITY (US) | 2022-02-15 | — | — | US | disclosed |
| US-6110929-A | IMMUNOMODULATORS WHICH INDUCE CYTOKINE BIOSYNTHESIS, INCLUDING INTERFERON AND/OR TUMOR BIOSYNTHESIS, NECROSIS FACTOR AND INHIBIT T-HELPER-TYPE 2 IMMUNE RESPONSE; FOR TREATMENT OF VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| WO-2000006577-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| US-5977366-A | 1-substituted, 2-substituted 1H-imidazo[4,5-c] quinolin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0582581-B1 | 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES | MINNESOTA MINING & MFG (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0872478-A2 | Intermediates for the preparation of 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5741909-A | PHARMACEUTICAL COMPOSITIONS WHICH ACT AS ANTIVIRAL AGENTS, INDUCE BIOSYNTHESIS OF INTERFERON AND INHIBIT TUMOR FORMATION IN ANIMALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5605899-A | VIRICIDES, BIOSYNTHESIS OF INTERFERONS, ANTITUMOR AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5389640-A | Viricides, antitumor agents | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| EP-0582581-A1 | 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO 4,5-c]QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-16 | — | — | EP | disclosed |
| WO-1992015582-A1 | 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177472-A1 | IMIDAZOQUINOLINE COMPOUNDS AND PRODRUGS THEREOF | TLR7, TLR8, TLR1 | TSHR 2531/4885MAPK1 1121/4885ALDH1A1 3874/4885 |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | MALT1, BCL6, BCL3 | TSHR 4796/4885MAPK1 523/4885ALDH1A1 3627/4885 |
| US-12295970-B2 | Imidazoquinoline compounds and prodrugs thereof | TLR7, TLR8, TLR1 | TSHR 2531/4885MAPK1 1121/4885ALDH1A1 3874/4885 |
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | FKBP2, FKBP14, FKBP1A | TSHR 3859/4885MAPK1 3962/4885ALDH1A1 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.