Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL1496269

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])O)[C@@H](O)[C@H]1O.[Na+].[Na+].[Na+]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 known ✓ P47900 9/20 0.75
P2RY2 known ✓ P41231 3/20 0.75
ADORA1 known ✓ P30542 1/20 0.75
PDE4D known ✓ Q08499 1/20 0.75
PDE3A known ✓ Q14432 1/20 0.75
SRC P12931 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
P2RX1 P51575 2/20 0.75
P2RX3 P56373 2/20 0.75
P2RX4 Q99571 1/20 0.75
P2RX2 Q9UBL9 1/20 0.75
ALDH1A1 P00352 1/20 0.75
ENPP1 P22413 4/20 0.75
P2RY11 Q96G91 3/20 0.75
TRPM2 O94759 2/20 0.75
DNPH1 O43598 1/20 0.75
PRKAB2 O43741 1/20 0.75
LDHA P00338 1/20 0.75
ADRB2 P07550 1/20 0.75
FBP1 P09467 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL30839398 1.00 P2RY1 (0.75) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL27568797 0.98 P2RY1 (0.73) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL30819483 0.98 P2RY1 (0.75) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL4734035 0.98 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL29723933 0.98 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL28791111 0.97 P2RY1 (0.74) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL11579601 0.97 P2RY1 (0.76) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL29803182 0.97 P2RY1 (0.76) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL30936667 0.97 P2RY1 (0.76) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL29444634 0.96 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11029457-A None JP disclosed
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof FERRER INTERNACIONAL, S.A. (ES) 2026-01-27 US disclosed
US-20220160744-A1 MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF FERRER INTERNACIONAL, S.A. (ES) 2022-05-26 US disclosed
EP-3965744-A1 MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF Ferrer Internacional, S.A. (ES) 2022-03-16 EP disclosed
CN-113784706-A Multi-layered pharmaceutical or nutraceutical solid dosage form comprising pyrimidine and/or purine derivatives and B vitamins, preparation and use thereof 菲尔若国际公司 2021-12-10 CN disclosed
CN-104592338-B A kind of method for synthesizing symmetric double ribonucleoside triphosphote, four phosphoric acid and five sodium ascorbyl phosphates 江西科技师范大学 2017-09-19 CN disclosed
EP-2301555-B1 CREAMY O/W EMULSION COMPOSITION AND PRODUCTION PROCESS THEREOF OTSUKA PHARMA CO LTD (JP) 2016-02-17 EP disclosed
CN-104592338-A Method for synthesizing symmetrical dual-core glycoside triphosphate, tetraphosphate and pentaphosphate sodium salts UNIV JIANGXI NORMAL SCI & TECH 2015-05-06 CN disclosed
CN-104262438-A Method for synthesizing symmetric bi-ribonucleoside triphosphate sodium salt, bi-ribonucleoside tetraphosphate sodium salt and bi-ribonucleoside pentaphosphates odium salt UNIV JIANGXI NORMAL SCI & TECH 2015-01-07 CN disclosed
US-8492360-B2 Creamy O/W emulsion composition and production process thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-07-23 US disclosed
CN-102046184-A Cream-like O/W type emulsified composition and method for producing same OTSUKA PHARMA CO LTD 2011-05-04 CN disclosed
EP-2301555-A1 CREAM-LIKE O/W TYPE EMULSIFIED COMPOSITION AND METHOD FOR PRODUCING SAME Otsuka Pharmaceutical Co., Ltd. (JP) 2011-03-30 EP disclosed
CN-100341486-C Oil-in-water type emulsion composition and method for producing the same OTSUKA PHARMA CO LTD (JP) 2007-10-10 CN disclosed
EP-1342462-B1 O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME OTSUKA PHARMA CO LTD (JP) 2007-04-11 EP disclosed
US-20060009415-A1 Corneal epithelial migration promoter NAKATA KATSUHIKO 2006-01-12 US disclosed
US-6946436-B2 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-09-20 US disclosed
CN-1476318-A Oil-in-water type emulsion composition and method for producing the same ��V��ҩ��ʽ���� 2004-02-18 CN disclosed
US-20040029761-A1 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-02-12 US disclosed
EP-1342462-A1 O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-09-10 EP disclosed
JP-H1129457-A SKIN COSMETIC KANEBO LTD 1999-02-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof P2RY10, TYMP, P2RY12 P2RY1 14/4885P2RY2 42/4885ADORA1 223/4885
US-20060009415-A1 Corneal epithelial migration promoter GPR17, UMPS, P2RY6 P2RY1 4/4885P2RY2 7/4885ADORA1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.