Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965789 | 0.85 | CYP1A2 (0.40) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL14965943 | 0.85 | GBA1 (0.40) | SORDPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14965984 | 0.82 | MAPT (0.42) | SORDPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14965774 | 0.81 | GBA1 (0.32) | TRPV1SORDPOLBALDH1A1CYP1A2 | |
| SCHEMBL14965834 | 0.80 | OGA (0.49) | OGAALDH1A1 | |
| SCHEMBL14965723 | 0.78 | AOC3 (0.39) | POLBALDH1A1 | |
| SCHEMBL14965871 | 0.78 | ALDH1A1 (0.42) | OGAPOLBALDH1A1 | |
| SCHEMBL14965636 | 0.77 | HRH4 (0.47) | OGAALDH1A1 | |
| SCHEMBL14965857 | 0.77 | ENPP2 (0.36) | TRPV1POLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14965978 | 0.77 | PARP1 (0.39) | TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |