Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,3-Dimercapto-1-Propanesulfonic Acid SCHEMBL27233595 | 0.77 | SLC22A6 (0.54) | KDM4EMAPTALOX15ENPEPSLC22A6 | |
| 2,3-Dimercapto-1-Propanesulfonic Acid SCHEMBL164318 | 0.77 | SLC22A6 (0.54) | KDM4EMAPTALOX15ENPEPSLC22A6 | |
| SCHEMBL28529173 | 0.76 | ENPEP (0.47) | KDM4EMAPTALOX15ENPEP | |
| 2,3-Dimercapto-1-Propanesulfonic Acid SCHEMBL1200081 | 0.75 | SLC22A6 (0.52) | KDM4EMAPTALOX15ENPEPSLC22A6 | |
| SCHEMBL125767 | 0.74 | KDM4E (0.32) | KDM4EMAPTALOX15 | |
| SCHEMBL1578142 | 0.74 | — | — | |
| SCHEMBL31634272 | 0.73 | ENPEP (0.50) | KDM4EMAPTALOX15ENPEP | |
| SCHEMBL27426173 | 0.73 | — | — | |
| SCHEMBL5608940 | 0.72 | — | — | |
| SCHEMBL18631090 | 0.72 | KDM4E (0.31) | KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160178574-A1 | TEST STRIP AND METHOD TO DETERMINE TEST STRIP COMPATIBILITY | CILAG GMBH INTERNATIONAL (CH) | 2016-06-23 | — | — | US | claimed |
| WO-2016097054-A2 | TEST STRIP AND METHOD TO DETERMINE TEST STRIP COMPATIBILITY | CILAG GMBH INTERNATIONAL (CH) | 2016-06-23 | — | — | WO | claimed |
| US-20160178574-A1 | TEST STRIP AND METHOD TO DETERMINE TEST STRIP COMPATIBILITY | CILAG GMBH INTERNATIONAL (CH) | 2016-06-23 | — | — | US | disclosed |
| WO-2016097054-A2 | TEST STRIP AND METHOD TO DETERMINE TEST STRIP COMPATIBILITY | CILAG GMBH INTERNATIONAL (CH) | 2016-06-23 | — | — | WO | disclosed |
| EP-2599799-B1 | SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING SAME | MITSUI CHEMICALS INC (JP) | 2016-05-25 | — | — | EP | disclosed |
| US-9034464-B2 | Single layer film and hydrophilic material comprising the same | MITSUI CHEMICALS, INC. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-20130156959-A1 | SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2013-06-20 | — | — | US | disclosed |
| EP-2599799-A1 | SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING SAME | Mitsui Chemicals, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |