SCHEMBL150790

SCHEMBL150790

CC(C#N)n1c2ccccc2c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.43
IMPDH2 P12268 1/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
MAPK1 P28482 2/20 0.40
ATM Q13315 2/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
EGFR P00533 1/20 0.37
SRC P12931 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
POLB P06746 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875976 0.87 MEN1 (0.41) BCHEACHEMAPK1MAPTCASP1
SCHEMBL11753437 0.85 MEN1 (0.53) MAPK1MAPTCASP1TDP1MEN1
SCHEMBL16468650 0.85 KMT2A (0.43) BCHEACHEMAPK1KMT2APOLB
SCHEMBL11603323 0.83 KDM4E (0.47) IMPDH2BCHEACHEMAPK1ATM
SCHEMBL11605581 0.78 CYP11B2 (0.38) MAPK1ATMMAPTTSHRCASP1
SCHEMBL11603371 0.78 ALDH1A1 (0.38) IMPDH2MAPK1ATMMAPTTSHR
SCHEMBL11606523 0.78 KDM4E (0.40) GPR3IMPDH2MAPK1ATMMAPT
SCHEMBL14076867 0.78 GPR3 (0.41) GPR3BCHEACHEMAPK1ATM
SCHEMBL11606236 0.77 LMNA (0.43) MAPK1MAPTMEN1KMT2ACYP1A2
SCHEMBL11826562 0.77 KDM4E (0.50) MAPK1MAPTTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3933849-A INDICATOR DYES AS OPTICAL FILTER AGENTS POLAROID CORPORATION (US) 1976-01-20 US claimed
JP-5230391-A None JP disclosed
US-11402560-B2 Method for producing laminated body SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-08-02 US disclosed
US-20210116619-A1 METHOD FOR PRODUCING LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-22 US disclosed
US-10890702-B2 Method for producing laminated body SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-12 US disclosed
WO-2020066831-A1 POLARIZING PLATE COMPOSITE AND IMAGE DISPLAY DEVICE 住友化学株式会社 2020-04-02 WO disclosed
US-10139540-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-27 US disclosed
US-20170358755-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-12-14 US disclosed
US-9541691-B2 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-10 US disclosed
US-9529130-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-27 US disclosed
US-8287767-B2 Amorphous polymers with pendant chromogenic groups E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
EP-2444391-A1 BASE AND RADICAL GENERATOR, COMPOSITION USING SAME AND METHOD FOR CURING SAME THREE BOND CO., LTD. (JP) 2012-04-25 EP disclosed
US-20120095124-A1 BASE AND RADICAL GENERATOR, COMPOSITION USING SAME AND METHOD FOR CURING SAME THREE BOND CO., LTD. (JP) 2012-04-19 US disclosed
US-20120057230-A1 POLARIZING PLATE MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
US-20090279160-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E. I. DUPONT DE NEMOURS AND COMPANY (US) 2009-11-12 US disclosed
EP-2032670-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-11 EP disclosed
WO-2007149090-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed
JP-H05230391-A WATER-INSOLUBLE MONOAZO DYE MITSUBISHI KASEI HOECHST KK 1993-09-07 JP disclosed
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-3933849-A INDICATOR DYES AS OPTICAL FILTER AGENTS POLAROID CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095124-A1 BASE AND RADICAL GENERATOR, COMPOSITION USING SAME AND METHOD FOR CURING SAME SRM, ARG2, SQOR GPR3 2691/4885IMPDH2 473/4885BCHE 2197/4885
US-20170358755-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ARL1, CCNL2, CRY1 GPR3 1333/4885IMPDH2 3859/4885BCHE 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.