SCHEMBL1509783

SCHEMBL1509783

CC(CNC(=N)N)C(C)(C)[C@@](C)(C(=O)O)N(C)S(=O)(=O)C1Cc2ccccc2O1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.30
OPRK1 P41145 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1509889 0.91 CA2 (0.35) CYP2D6OPRK1
SCHEMBL27228693 0.73 MMP2 (0.44)
SCHEMBL4297055 0.73 MMP2 (0.44)
SCHEMBL7262682 0.71 KEAP1 (0.43)
SCHEMBL13936947 0.60 GPBAR1 (0.46)
SCHEMBL8998762 0.60 LMNA (0.40)
SCHEMBL28374258 0.60 BCAT2 (0.33)
SCHEMBL11072331 0.59 HPGD (0.43)
SCHEMBL7748074 0.59 CA2 (0.44)
SCHEMBL7279348 0.59 SSTR4 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897721-B2 Cyclic peptide compositions for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2011-03-01 US disclosed
US-20100121027-A1 Cyclic Peptide Compositions for Treatment of Sexual Dysfunction PALATIN TECHNOLOGIES, INC. (US) 2010-05-13 US disclosed
US-7176279-B2 Cyclic peptide compositions and methods for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2007-02-13 US disclosed
EP-1667700-A2 CYCLIC PEPTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF SEXUAL DYSFUNCTION Palatin Technologies, Inc. (US) 2006-06-14 EP disclosed
WO-2005014617-A2 CYCLIC PEPTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF SEXUAL DYSFUNCTION PALATIN TECHNOLOGIES, INC. (US) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100121027-A1 Cyclic Peptide Compositions for Treatment of Sexual Dysfunction VIP, GNRHR, NPR1 CYP2D6 4277/4885OPRK1 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.