Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15112808 | 0.84 | GBA1 (0.31) | GBA1CTSLCTSB | |
| SCHEMBL7900305 | 0.76 | CTSL (0.37) | GBA1CTSLCTSB | |
| SCHEMBL15112811 | 0.74 | L3MBTL1 (0.33) | — | |
| SCHEMBL1114588 | 0.73 | CTSL (0.42) | GBA1CTSLCTSB | |
| SCHEMBL106833 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL8169577 | 0.72 | TDP1 (0.47) | — | |
| SCHEMBL15112809 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL15631188 | 0.71 | THRB (0.32) | — | |
| SCHEMBL26512339 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL12790596 | 0.70 | CTSL (0.40) | GBA1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297738-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20140088298-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140073602-A9 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20140073778-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20140073779-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20130217871-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130211060-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130184237-A1 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20130184454-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20130184455-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088298-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HACL2, HASPIN, LIPA | GBA1 163/4885CTSL 21/4885CTSB 977/4885 |
| US-20130211060-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HACL2, HASPIN, LIPA | GBA1 163/4885CTSL 21/4885CTSB 977/4885 |
| US-20130184237-A1 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES | NOS2, NOS3, NOS1 | GBA1 770/4885CTSL 2498/4885CTSB 2983/4885 |
| US-20140073602-A9 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES | NOS2, NOS3, NOS1 | GBA1 770/4885CTSL 2498/4885CTSB 2983/4885 |
| US-20150297738-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HASPIN, HACL2, PCNA | GBA1 100/4885CTSL 96/4885CTSB 736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.