SCHEMBL15152

SCHEMBL15152

C=C(C)C(=O)OC(Cn1c(=O)[nH]c(=O)[nH]c1=O)(OC(=O)C(=C)C)OC(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16227843 0.98 TSHR (0.32) TSHR
SCHEMBL328926 0.86 TSHR (0.32) TSHR
SCHEMBL7708748 0.78 GAA (0.34) ALDH1A1
SCHEMBL149919 0.77 THRB (0.37) TSHRALDH1A1
SCHEMBL2488022 0.76
SCHEMBL28004954 0.76 TSHR (0.43) TSHRALDH1A1
Methacrylic Acid SCHEMBL904578 0.74 APEX1 (0.33)
Methacrylic Acid SCHEMBL1008210 0.74 APEX1 (0.33)
SCHEMBL9696445 0.74 TSHR (0.32) TSHR
SCHEMBL831001 0.73 THRB (0.42) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1011 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4035647-B1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-10-18 EP claimed
US-11584827-B2 Photopolymerizable compositions including a urethane component and a reactive diluent, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-21 US claimed
WO-2023278202-A1 NOVEL URETHANE ACRYLATE COMPOSITION COVESTRO LLC (US) 2023-01-05 WO claimed
US-20220411560-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS INC. 2022-12-29 US claimed
EP-2152224-B1 SELF-HEALING DENTAL COMPOSITES PREMIER DENTAL PRODUCTS CO (US) 2022-08-17 EP claimed
US-20200140614-A1 PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A URETHANE COMPONENT AND A REACTIVE DILUENT, ARTICLES, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-05-07 US claimed
US-20180016365-A1 CO-INITIATOR AND CO-MONOMER FOR USE IN PREPARING POLYMER RELATED COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE UNIVERSITY OF KANSAS 2018-01-18 US claimed
WO-2016149488-A1 CO-INITIATOR AND CO-MONOMER FOR USE IN PREPARING POLYMER RELATED COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE UNIVERSITY OF KANSAS (US) 2016-09-22 WO claimed
US-9155685-B2 Low stress flowable dental composition DENTSPLY INTERNATIONAL INC. (US) 2015-10-13 US claimed
US-20110082232-A1 Self-healing dental restorative formulations and related methods FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2011-04-07 US claimed
US-20110071234-A1 Self-Healing dental restorative formulations and related methods FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2011-03-24 US claimed
WO-2010021476-A2 PHOTOPOLYMERIZABLE OLIGOMER, PHOTOPOLYMERIZABLE RESIN COMPOSITION CONTAINING THE SAME, AND OPTICAL FIBER 에스에스씨피 주식회사 (KR) 2010-02-25 WO claimed
US-20090247660-A1 NOVEL MONOMER FOR DENTAL COMPOSITIONS UNIVERSITY OF KANSAS 2009-10-01 US claimed
US-20080300340-A1 Self-healing dental composites and related methods FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2008-12-04 US claimed
US-20070004864-A1 Method to enhance impact strength properties of melt processed polypropylene resins UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2007-01-04 US claimed
US-20050042515-A1 Composition for protecting negative electrode for lithium metal battery, and lithium metal battery fabricated using same SAMSUNG SDI CO., LTD. (KR) 2005-02-24 US claimed
US-6159012-A Process for treating hard tissues 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-12 US claimed
US-4882389-A CURED BUTADIENE POLYMER MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1989-11-21 US claimed
US-4652619-A Epoxy impregnating resin composition MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1987-03-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180016365-A1 CO-INITIATOR AND CO-MONOMER FOR USE IN PREPARING POLYMER RELATED COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CAD, JMJD6, MMAB TSHR 4803/4885ALDH1A1 211/4885
US-20090247660-A1 NOVEL MONOMER FOR DENTAL COMPOSITIONS MACF1, PPIP5K2, MEP1A TSHR 2824/4885ALDH1A1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.