SCHEMBL15400071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29254216	0.84	LIPG (0.57)	LPLLIPGDGAT1IRAK4NPC1
	SCHEMBL27343841	0.79	LPL (0.40)	LPLLIPGCYP1A2IRAK4NPC1
	SCHEMBL27343624	0.79	LPL (0.40)	LPLLIPGCYP1A2PDPK1IRAK4
	SCHEMBL17379035	0.73	CA12 (0.40)	NPC1RAB9AALPL
	SCHEMBL24553447	0.73	PIM1 (0.37)	RAB9ACHEK1
	SCHEMBL360717	0.73	LPL (0.49)	LPLLIPGDGAT1IRAK4ALPL
	SCHEMBL17413790	0.73	LPL (0.49)	LPLLIPGCYP1A2CYP2A6DGAT1
	SCHEMBL15906932	0.72	LPL (0.42)	LPLLIPGDGAT1IRAK4ALPL
	SCHEMBL20295219	0.72	ALDH1A1 (0.40)	LPLLIPGNPC1RAB9AALPL
	SCHEMBL12496248	0.72	LPL (0.41)	LPLLIPGCYP1A2CYP2A6IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.