Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955480 | 0.74 | CES2 (0.53) | RAB9ANPC1ALDH1A1CES2CES1 | |
| Dimethylamine SCHEMBL28473067 | 0.71 | CES2 (0.57) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL4132169 | 0.70 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5227559 | 0.69 | DAO (0.53) | RAB9ANPC1ALDH1A1CES2CES1 | |
| Hydrochloric Acid SCHEMBL6251045 | 0.68 | DAO (0.52) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL5050004 | 0.68 | TSHR (0.51) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL1937375 | 0.68 | RAB9A (0.58) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL619898 | 0.68 | CES2 (0.64) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL8522700 | 0.68 | CTSK (0.46) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL15974627 | 0.67 | ALDH1A1 (0.62) | RAB9ANPC1ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357874-A1 | PROCESS FOR PREPARING (S)-3-N-METHYLAMINO-1-(2-THIENYL)-1-PROPANOL | SALTIGO GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140031564-A1 | PROCESS FOR PREPARING (S)-3-N-METHYLAMINO-1-(2-THIENYL)-1-PROPANOL | SALTIGO GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357874-A1 | PROCESS FOR PREPARING (S)-3-N-METHYLAMINO-1-(2-THIENYL)-1-PROPANOL | PNMT, SULT1A1, CYP51A1 | RAB9A 3227/4885NPC1 547/4885ALDH1A1 192/4885 |
| US-20140031564-A1 | PROCESS FOR PREPARING (S)-3-N-METHYLAMINO-1-(2-THIENYL)-1-PROPANOL | PNMT, SULT1A1, CYP51A1 | RAB9A 3227/4885NPC1 547/4885ALDH1A1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.