Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547855 | 0.83 | CA3 (0.38) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL98914 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL9545003 | 0.78 | HSPB1 (0.39) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL1321164 | 0.77 | NFE2L2 (0.48) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL29366053 | 0.75 | LMNA (0.53) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL197204 | 0.75 | LMNA (0.53) | ALDH1A1MEN1HPGDKMT2APOLB | |
| SCHEMBL10456772 | 0.74 | TRPA1 (0.56) | ALDH1A1TRPA1HSPB1 | |
| SCHEMBL1342628 | 0.72 | AKR1B1 (0.32) | — | |
| SCHEMBL27583374 | 0.72 | HSPB1 (0.50) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL13177071 | 0.71 | TRPA1 (0.41) | ALDH1A1MEN1HPGDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311816-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2311817-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2308858-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | CYP4X1, PRDX5, PRDX1 | ALDH1A1 1299/4885MEN1 4632/4885HPGD 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.