Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.78 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NCF1 | P14598 | 1/20 | 0.60 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7406183 | 0.98 | HRH3 (0.75) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL8244456 | 0.98 | HRH3 (0.74) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL4277270 | 0.89 | HRH3 (1.00) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL3040325 | 0.88 | HRH3 (0.70) | HRH3HRH4POLBCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7468055 | 0.86 | HRH3 (0.95) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL11201497 | 0.86 | HRH3 (0.94) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL11196296 | 0.84 | HRH3 (0.90) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL13062773 | 0.83 | HRH3 (0.72) | HRH3HRH4ALDH1A1KDM4EPOLB | |
| SCHEMBL19671018 | 0.83 | CHKA (0.77) | ALDH1A1KDM4EPOLBNCF1 | |
| SCHEMBL329323 | 0.83 | HRH3 (0.78) | HRH3HRH4ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230174933-A1 | METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS | NOVARTIS AG (CH) | 2023-06-08 | — | — | US | disclosed |
| US-11584805-B2 | Oligosaccharide compositions and methods for producing thereof | DSM NUTRITIONAL PRODUCTS, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220251152-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2022-08-11 | — | — | US | disclosed |
| US-20210317107-A1 | INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-14 | — | — | US | disclosed |
| US-20210002387-A1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | HERCULES CAPITAL, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20190307159-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS FOOD INGREDIENTS AND METHODS OF PRODUCING THEREOF | HERCULES CAPITAL, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10329257-B2 | Compositions and methods for treating tuberculosis | THE BROAD INSTITUTE, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-20190038600-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DEISEASES | BOEHRINGER INGELHEIM INT (DE) | 2019-02-07 | — | — | US | disclosed |
| EP-2258356-B1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2017-09-27 | — | — | EP | disclosed |
| WO-2009158587-A1 | METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITOR COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009155209-A1 | OPHTHALMIC FORMULATION OF RHO KINASE INHIBITOR COMPOUND | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2008145681-A2 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008077057-A2 | CYTOSKELETAL ACTIVE RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329257-B2 | Compositions and methods for treating tuberculosis | C5, IFNG, TERT | HRH3 2194/4885HRH4 1456/4885ALDH1A1 1848/4885 |
| US-20210002387-A1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | OSTC, FUT5, FUT6 | HRH3 3895/4885HRH4 3871/4885ALDH1A1 2641/4885 |
| US-11584805-B2 | Oligosaccharide compositions and methods for producing thereof | OSTC, FUT5, FUT6 | HRH3 3895/4885HRH4 3871/4885ALDH1A1 2641/4885 |
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | HRH3 303/4885HRH4 120/4885ALDH1A1 2458/4885 |
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | MMP1, COL1A1, SMAD3 | HRH3 380/4885HRH4 368/4885ALDH1A1 174/4885 |
| US-20190038600-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DEISEASES | MMP1, COL1A1, IDO1 | HRH3 335/4885HRH4 253/4885ALDH1A1 200/4885 |
| US-20210317107-A1 | INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | MELK, HIPK1, HIPK3 | HRH3 2877/4885HRH4 3749/4885ALDH1A1 3459/4885 |
| US-20230174933-A1 | METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS | HAVCR2, MICA, CD74 | HRH3 2526/4885HRH4 3991/4885ALDH1A1 3289/4885 |
| US-20220251152-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | RPS27A, PSMG3, PREP | HRH3 3656/4885HRH4 3890/4885ALDH1A1 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.