SCHEMBL1551922

SCHEMBL1551922

CCCCCCCCC#CCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.56
HMGCR P04035 3/20 0.56
RECQL P46063 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
BLM P54132 1/20 0.47
MCL1 Q07820 1/20 0.47
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.46
EPHX2 P34913 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7341770 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL7350770 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL487742 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL9496128 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL23014964 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL15766733 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL23015081 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL1537343 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL1537174 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL1550995 1.00 PTPN7 (0.56) PTPN7HMGCRRECQLTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622891-B2 AMP-activated protein kinase activator KYOTO PHARMACEUTICAL UNIVERSITY (JP) 2026-05-12 US disclosed
WO-2025077836-A1 IONIZABLE LIPIDS AND LIPID NANOPARTICLES FOR RNA DELIVERY BEIGENE SWITZERLAND GMBH (CH) 2025-04-17 WO disclosed
EP-4281433-B1 INCENSE ODORANT FIRMENICH & CIE (CH) 2024-12-25 EP disclosed
CN-116444464-B Method for asymmetrically synthesizing inchworm sex pheromone 中国农业大学 2024-11-22 CN disclosed
US-20240277657-A1 NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR KYOTO PHARMACEUTICAL UNIVERSITY (JP) 2024-08-22 US disclosed
US-20240199524-A1 INCENSE ODORANT FIRMENICH & CIE (CH) 2024-06-20 US disclosed
EP-4349331-A1 NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR Kyoto Pharmaceutical University (JP) 2024-04-10 EP disclosed
CN-117794527-A Novel AMP-activating protein kinase activators 学校法人京都药科大学 2024-03-29 CN disclosed
US-20240050378-A1 LIPID NANOPARTICLE COMPOSITIONS CONTAINING MONOESTER CATIONIC LIPIDS MERCK SHARP & DOHME LLC (US) 2024-02-15 US disclosed
EP-4281433-A1 INCENSE ODORANT Firmenich SA (CH) 2023-11-29 EP disclosed
WO-2016079431-A1 2-OCTYLCYCLOPROPYL-1-CARBOXYLIC ACID AND THE ISOMERS THEREOF, AND USES OF SAME ALBERT VIEILLE (FR) 2016-05-26 WO disclosed
US-8445511-B2 Quinoline or quinoxaline derivatives for treating neurodegenerative diseases Centre National de la Recherche Scientifique (SNRS) (FR) 2013-05-21 US disclosed
US-20110118270-A1 HETEROCYCLIC DERIVATIVES THAT ARE USED IN THE TREATMENT OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) 2011-05-19 US disclosed
EP-2313373-A1 HETEROCYCLIC DERIVATIVES THAT ARE USED IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Centre National de la Recherche Scientifique (C.N.R.S) (FR) 2011-04-27 EP disclosed
WO-2010007179-A1 HETEROCYCLIC DERIVATIVES THAT ARE USED IN THE TREATMENT OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-01-21 WO disclosed
EP-0483851-B1 Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives MITSUBISHI CHEM CORP (JP) 1996-03-13 EP disclosed
WO-1993025521-A1 ARYL ALIPHATIC ACIDS BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1993-12-23 WO disclosed
US-5238832-A Lipoxygenase inhibitors BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1993-08-24 US disclosed
US-5128350-A PYRAZOLYL ACRYLIC ACID DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING SAID DERIVATIVES MITSUBISHI KASEI CORPORATION (JP) 1992-07-07 US disclosed
EP-0483851-A1 Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives Mitsubishi Chemical Corporation (JP) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199524-A1 INCENSE ODORANT OPRM1, CPT1A, TAS2R5 PTPN7 4844/4885HMGCR 1802/4885RECQL 3593/4885
US-12622891-B2 AMP-activated protein kinase activator PRKAA1, PRKAG1, PRKAB1 PTPN7 1234/4885HMGCR 3962/4885RECQL 2297/4885
US-20240277657-A1 NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR PRKAG1, PRKAG2, PRKAB1 PTPN7 1882/4885HMGCR 4613/4885RECQL 1856/4885
US-20240050378-A1 LIPID NANOPARTICLE COMPOSITIONS CONTAINING MONOESTER CATIONIC LIPIDS LIPA, LIPC, MGLL PTPN7 1984/4885HMGCR 305/4885RECQL 1697/4885
US-20110118270-A1 HETEROCYCLIC DERIVATIVES THAT ARE USED IN THE TREATMENT OF NEURODEGENERATIVE DISEASES HCRTR2, HCRTR1, CHRNA2 PTPN7 4301/4885HMGCR 634/4885RECQL 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.