Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629629 | 0.86 | TSHR (0.39) | THRB | |
| SCHEMBL27748757 | 0.83 | DNM1 (0.39) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL22207367 | 0.83 | CHRM2 (0.37) | CHRM1CHRM2CHRM3 | |
| SCHEMBL26980911 | 0.81 | ACHE (0.37) | SMN1; SMN2ALDH1A1GAATHRB | |
| SCHEMBL937816 | 0.79 | GLO1 (0.42) | SMN1; SMN2MAPTNPSR1ALDH1A1CYP2C19 | |
| SCHEMBL340908 | 0.78 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL28150485 | 0.78 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL8007103 | 0.78 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL28968670 | 0.78 | THRB (0.49) | CA1CA2ALDH1A1THRB | |
| Water SCHEMBL21326730 | 0.77 | CHRM1 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4299133-A2 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | VIIV Healthcare Company (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20220211714-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2022-07-07 | — | — | US | disclosed |
| US-11311545-B2 | Compositions and methods for the delivery of therapeutics | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2022-04-26 | — | — | US | disclosed |
| US-11117904-B2 | Compositions and methods for the delivery of therapeutics | VIIV HEALTHCARE COMPANY (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210230186-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | VIIV HEALTHCARE COMPANY | 2021-07-29 | — | — | US | disclosed |
| US-10400262-B2 | Analyte sensing for eye injuries and conditions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-09-03 | — | — | US | disclosed |
| EP-3474857-A2 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | VIIV Healthcare Company (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180105857-A1 | Analyte Sensing for Eye Injuries and Conditions | CARLE HEALTH CARE INCORPORATED D/B/A CARLE PHYSICIAN GROUP | 2018-04-19 | — | — | US | disclosed |
| WO-2017223280-A2 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | VIIV HEALTHCARE COMPANY (US) | 2017-12-28 | — | — | WO | disclosed |
| US-20170304308-A1 | Compositions and Methods for the Delivery of Therapeutics | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2017-10-26 | — | — | US | disclosed |
| EP-3203995-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | Board of Regents of the University of Nebraska (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20170165271-A1 | Compositions and Methods for the Delivery of Therapeutics | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2017-06-15 | — | — | US | disclosed |
| EP-3110422-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | Board of Regents of the University of Nebraska (US) | 2017-01-04 | — | — | EP | disclosed |
| US-20160136105-A1 | Compositions and Methods for the Delivery of Therapeutics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-05-19 | — | — | US | disclosed |
| WO-2016057866-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2016-04-14 | — | — | WO | disclosed |
| WO-2015127437-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2015-08-27 | — | — | WO | disclosed |
| US-20150151006-A1 | Compositions and Methods for Gene Therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-04 | — | — | US | disclosed |
| US-20150125401-A1 | SMALL MAGNETITE THERAPEUTICS AND METHODS OF USE THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2015-05-07 | — | — | US | disclosed |
| US-20150079007-A1 | TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2015-03-19 | — | — | US | disclosed |
| WO-2013159092-A1 | TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2013-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230186-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-20160136105-A1 | Compositions and Methods for the Delivery of Therapeutics | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-20150079007-A1 | TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF | CD47, AIP, PSMA3 | CHRM1 2809/4885CHRM2 3353/4885CHRM4 3587/4885 |
| US-20170304308-A1 | Compositions and Methods for the Delivery of Therapeutics | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-11117904-B2 | Compositions and methods for the delivery of therapeutics | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-20170165271-A1 | Compositions and Methods for the Delivery of Therapeutics | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-11311545-B2 | Compositions and methods for the delivery of therapeutics | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
| US-20220211714-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS | HAVCR2, MTREX, MAVS | CHRM1 4845/4885CHRM2 4775/4885CHRM4 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.