Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527560 | 1.00 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527562 | 1.00 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL30583265 | 0.90 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527596 | 0.85 | TDP1 (0.45) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL16787367 | 0.85 | TDP1 (0.41) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL22477320 | 0.85 | TDP1 (0.41) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527599 | 0.85 | TDP1 (0.45) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527598 | 0.85 | TDP1 (0.45) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL23718791 | 0.83 | MAOB (0.42) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21780047 | 0.83 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984996-B1 | AMINO PYRIMIDINE SSAO INHIBITORS | LILLY CO ELI (US) | 2024-10-09 | — | — | EP | claimed |
| CN-114380801-A | Aminopyrimidine SSAO inhibitors and methods of making the same | 伊莱利利公司 | 2022-04-22 | — | — | CN | claimed |
| EP-3984996-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | Eli Lilly and Company (US) | 2022-04-20 | — | — | EP | claimed |
| CN-114369095-A | Aminopyrimidine compounds useful as SSAO inhibitors and methods of making the same | 伊莱利利公司 | 2022-04-19 | — | — | CN | claimed |
| US-10793552-B2 | Amino pyrimidine ssao inhibitors | ELI LILLY AND COMPANY (US) | 2020-10-06 | — | — | US | claimed |
| US-20200262817-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2020-08-20 | — | — | US | claimed |
| US-10471060-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | ELI LILLY AND COMPANY (US) | 2019-11-12 | — | — | US | claimed |
| US-10464928-B2 | Amino pyrimidine SSAO inhibitors | ELI LILLY AND COMPANY (US) | 2019-11-05 | — | — | US | claimed |
| US-20190276436-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2019-09-12 | — | — | US | claimed |
| US-20190275041-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2019-09-12 | — | — | US | claimed |
| US-12486244-B2 | Preparation of semicarbazide-sensitive amine oxidase inhibitor and use thereof | ENNOVABIO (ZHEJIANG) PHARMACEUTICALS CO., LTD. (CN) | 2025-12-02 | — | — | US | disclosed |
| US-12428370-B2 | Haloallylamine dual amine oxidase inhibitors | SYNTARA LIMITED (AU) | 2025-09-30 | — | — | US | disclosed |
| US-12371432-B2 | Haloallylamine compounds and application thereof | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2025-07-29 | — | — | US | disclosed |
| US-12258336-B2 | Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| EP-4501323-A2 | AMINO PYRIMIDINE SSAO INHIBITORS | Eli Lilly and Company (US) | 2025-02-05 | — | — | EP | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| EP-2844637-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PharmAxis Ltd (AU) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013163675-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PHARMAXIS LTD. (AU) | 2013-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486244-B2 | Preparation of semicarbazide-sensitive amine oxidase inhibitor and use thereof | MAOB, MAOA, AOC3 | TDP1 1745/4885MAOA 2/4885MAOB 1/4885 |
| US-12371432-B2 | Haloallylamine compounds and application thereof | ADRA1D, ADRA1A, VAPA | TDP1 167/4885MAOA 485/4885MAOB 886/4885 |
| US-20200262817-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | DPYD, NUDT1, SLC28A1 | TDP1 243/4885MAOA 1346/4885MAOB 570/4885 |
| US-20190276436-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | DPYD, NUDT1, SLC28A1 | TDP1 430/4885MAOA 1015/4885MAOB 477/4885 |
| US-12428370-B2 | Haloallylamine dual amine oxidase inhibitors | AOC2, AOC3, AOC1 | TDP1 176/4885MAOA 6/4885MAOB 4/4885 |
| US-10471060-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | DPYD, TYMP, NUDT1 | TDP1 663/4885MAOA 587/4885MAOB 255/4885 |
| US-10793552-B2 | Amino pyrimidine ssao inhibitors | DPYD, NUDT1, SLC28A1 | TDP1 242/4885MAOA 1295/4885MAOB 542/4885 |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | HAO1, VAPA, AOC3 | TDP1 479/4885MAOA 206/4885MAOB 524/4885 |
| US-10464928-B2 | Amino pyrimidine SSAO inhibitors | DPYD, NUDT1, SLC28A1 | TDP1 242/4885MAOA 1295/4885MAOB 542/4885 |
| US-12258336-B2 | Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof | MAOB, MAOA, SMOX | TDP1 2229/4885MAOA 2/4885MAOB 1/4885 |
| US-20190275041-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | DPYD, TYMP, NUDT1 | TDP1 663/4885MAOA 587/4885MAOB 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.