Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527599 | 1.00 | TDP1 (0.45) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527598 | 1.00 | TDP1 (0.45) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL30583342 | 0.87 | TDP1 (0.46) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL16787367 | 0.86 | TDP1 (0.41) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL22477320 | 0.86 | TDP1 (0.41) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL24058357 | 0.86 | TDP1 (0.47) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21615026 | 0.85 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21780047 | 0.85 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21615025 | 0.85 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15527738 | 0.85 | TDP1 (0.40) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768675-B1 | NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2026-04-01 | — | — | EP | disclosed |
| CN-112955214-B | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11780830-B2 | Triazolone derivatives or salts thereof and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2023-10-10 | — | — | US | disclosed |
| EP-3873599-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-27 | — | — | EP | disclosed |
| US-11492335-B2 | Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2022-11-08 | — | — | US | disclosed |
| US-11332436-B2 | Processes for preparing (E)-(2-(chloromethyl)-3-fluoroallyl) carbamate compounds | YUHAN CORPORATION (KR) | 2022-05-17 | — | — | US | disclosed |
| US-20210353608-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| US-20210238192-A1 | VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20210230103-A1 | PROCESSES FOR PREPARING (E)-(2-(CHLOROMETHYL)-3-FLUOROALLYL) CARBAMATE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-07-29 | — | — | US | disclosed |
| CN-112955214-A | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20160244406-A1 | Substituted 3-Haloallylamine Inhibitors of SSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160244406-A1 | Substituted 3-Haloallylamine Inhibitors of SSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-9302986-B2 | Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-9302986-B2 | Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-9302986-B2 | Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
| EP-2844637-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PharmAxis Ltd (AU) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013163675-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PHARMAXIS LTD. (AU) | 2013-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492335-B2 | Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same | CYP7A1, NAT1, NCOA1 | TDP1 413/4885MAOA 708/4885MAOB 867/4885 |
| US-20210238192-A1 | VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF | VCAM1, VAPB, ICAM1 | TDP1 2776/4885MAOA 2312/4885MAOB 2301/4885 |
| US-20210353608-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ARSA, SULT1A1, SULT2A1 | TDP1 3078/4885MAOA 361/4885MAOB 673/4885 |
| US-20160244406-A1 | Substituted 3-Haloallylamine Inhibitors of SSAO and uses thereof | AOC3, HAO1, VAPA | TDP1 399/4885MAOA 106/4885MAOB 212/4885 |
| US-11780830-B2 | Triazolone derivatives or salts thereof and pharmaceutical compositions comprising the same | SLC10A1, VAT1, LIPC | TDP1 399/4885MAOA 1624/4885MAOB 1784/4885 |
| US-20210230103-A1 | PROCESSES FOR PREPARING (E)-(2-(CHLOROMETHYL)-3-FLUOROALLYL) CARBAMATE COMPOUNDS | CTSL, EML4, CTSE | TDP1 2085/4885MAOA 1642/4885MAOB 1198/4885 |
| US-11332436-B2 | Processes for preparing (E)-(2-(chloromethyl)-3-fluoroallyl) carbamate compounds | CTSL, EML4, CTSE | TDP1 2085/4885MAOA 1642/4885MAOB 1198/4885 |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | HAO1, VAPA, AOC3 | TDP1 479/4885MAOA 206/4885MAOB 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.