Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.58 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.71 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.71 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | CD40LG | P29965 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545001 | 1.00 | PRMT1 (0.71) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL4166243 | 0.89 | PRMT1 (0.61) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL3698096 | 0.89 | PRMT1 (0.61) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL29770470 | 0.88 | PRMT1 (0.61) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL27789115 | 0.86 | PRMT1 (0.54) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL14388947 | 0.83 | PRMT1 (0.53) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL29642565 | 0.82 | THRB (0.56) | PRMT1CARM1THRBENPP2FUT8 | |
| SCHEMBL14388852 | 0.82 | PRMT1 (0.53) | PRMT1CARM1THRBCD40CD40LG | |
| SCHEMBL11671160 | 0.81 | PRMT1 (0.68) | PRMT1CARM1CD40CD40LGENPP2 | |
| SCHEMBL14388920 | 0.79 | FUT8 (0.54) | PRMT1CARM1THRBCD40CD40LG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | claimed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | claimed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | claimed |
| EP-3390708-B1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO KGAA (DE) | 2023-04-05 | — | — | EP | disclosed |
| EP-3390708-A1 | CONSUMER UNIT FOR DYEING TEXTILE | Henkel AG & Co. KGaA (DE) | 2018-10-24 | — | — | EP | disclosed |
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017102314-A1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO. KGAA (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | disclosed |