Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626417 | 1.00 | MAPT (0.38) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL20563667 | 0.87 | NCEH1 (0.47) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29560409 | 0.80 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19SLC2A1 | |
| SCHEMBL635407 | 0.80 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19SLC2A1 | |
| SCHEMBL30706241 | 0.80 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20563974 | 0.79 | MAPT (0.37) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL7709361 | 0.79 | MAPT (0.37) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL31375043 | 0.78 | MAPT (0.46) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17048014 | 0.78 | DRD2 (0.39) | KDM4EALDH1A1DRD2DRD3DRD4 | |
| SCHEMBL15565904 | 0.78 | DRD2 (0.32) | KDM4EHSD11B1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230087351-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO- 9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | UNIVERSITY OF SALFORD (GB) | 2023-03-23 | — | — | US | disclosed |
| CN-114423754-A | Antiviral agents and uses thereof | 格里菲斯大学 | 2022-04-29 | — | — | CN | disclosed |
| US-20210323987-A1 | Methods for the Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-21 | — | — | US | disclosed |
| WO-2021116686-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO-9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | UNIVERSITY OF LANCASTER (GB) | 2021-06-17 | — | — | WO | disclosed |
| WO-2020041369-A1 | METHODS FOR THE SYNTHESIS OF HETEROATOM CONTAINING POLYCYCLIC AROMATIC HYDROCARBONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-02-27 | — | — | WO | disclosed |
| EP-2880041-B1 | PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS | COUNCIL SCIENT IND RES (IN) | 2018-10-10 | — | — | EP | disclosed |
| US-9920070-B2 | Spiro-oxazines, indolinones and preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-03-20 | — | — | US | disclosed |
| US-20170174706-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-22 | — | — | US | disclosed |
| US-9617280-B2 | Spiro-oxazines, indolinones and preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-04-11 | — | — | US | disclosed |
| US-20160115179-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-9200018-B2 | Process for preparation of aryl phosphorous compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20150210725-A1 | PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-30 | — | — | US | disclosed |
| EP-2880041-A1 | PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS | Council of Scientific & Industrial Research (IN) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014184808-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014024212-A1 | PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174706-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | NR3C2, AR, REN | MAPT 2883/4885CYP1A2 368/4885CYP2C9 462/4885 |
| US-20210323987-A1 | Methods for the Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons | AHR, PAH, ALKBH3 | MAPT 4225/4885CYP1A2 54/4885CYP2C9 182/4885 |
| US-20150210725-A1 | PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS | PFAS, PAICS, INPP5B | MAPT 2473/4885CYP1A2 936/4885CYP2C9 1119/4885 |
| US-20160115179-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | NR3C2, AR, REN | MAPT 2883/4885CYP1A2 368/4885CYP2C9 462/4885 |
| US-20230087351-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO- 9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | INMT, AZI2, OPRD1 | MAPT 1140/4885CYP1A2 478/4885CYP2C9 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.