SCHEMBL15745922

SCHEMBL15745922

[N-]=[N+]=Nc1ccccc1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.33
GAA P10253 3/20 0.33
NPC1 O15118 3/20 0.33
MAPK1 P28482 2/20 0.33
ACHE P22303 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LRRK2 Q5S007 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
RAB9A P51151 2/20 0.33
USP2 O75604 1/20 0.33
NFE2L2 Q16236 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28948577 0.82 REV1 (0.40) CES2CES1
SCHEMBL27630601 0.82 GABRA1 (0.34) MAPTGAANPC1KDM4EL3MBTL1
SCHEMBL30858726 0.82 GABRA1 (0.34) MAPTGAANPC1KDM4EL3MBTL1
SCHEMBL22604933 0.80 MAPT (0.31) MAPTGAANPC1MAPK1KDM4E
SCHEMBL28459050 0.79 REV1 (0.34) GAA
SCHEMBL15733288 0.76 HTR3E (0.45) MAPTNPC1L3MBTL1MEN1KMT2A
SCHEMBL29365405 0.76 HTR3E (0.45) MAPTNPC1L3MBTL1MEN1KMT2A
SCHEMBL23355905 0.75 GABRA1 (0.41) MAPK1L3MBTL1GABRA1GABRG2GABRB3
SCHEMBL28674655 0.74 CA12 (0.38) MAPTGAAMAPK1KDM4EMEN1
SCHEMBL14691418 0.74 HTR3E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113773204-B Preparation method of fluoroaniline 上海万溯药业有限公司 2024-04-16 CN claimed
CN-113773204-A Preparation method of fluoroaniline 上海万溯药业有限公司 2021-12-10 CN claimed
CN-107043335-A A kind of preparation method of 2 fluorophenyl azido compound 湖南华腾制药有限公司 2017-08-15 CN claimed
US-12612409-B2 Pyrrolopyrimidines as CFTR potentiators CYSTIC FIBROSIS FOUNDATION (US) 2026-04-28 US disclosed
US-20260033119-A1 A PHOTONIC-ORGANIC ELECTROCHEMICAL TRANSISTOR PURDUE RESEARCH FOUNDATION (US) 2026-01-29 US disclosed
US-12473263-B2 Bicyclic inhibitors of CBX chromodomains ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-11-18 US disclosed
US-12466811-B2 Mass spectrometry cleavable heterobifunctional photoactivated cross-linkers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-11 US disclosed
WO-2025063899-A1 A DYNAMIC CROSSLINKER, COVALENT ADAPTABLE NETWORK COMPRISING POLYMER NETWORK CROSSLINKED BY SAID DYNAMIC CROSSLINKER AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-03-27 WO disclosed
WO-2024187047-A1 A PHOTONIC-ORGANIC ELECTROCHEMICAL TRANSISTOR PURDUE RESEARCH FOUNDATION (US) 2024-09-12 WO disclosed
EP-4424311-A2 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS Cystic Fibrosis Foundation (US) 2024-09-04 EP disclosed
CN-118420815-A Polybutadiene polymer containing fluorophenyl azide/perfluorophenyl, preparation method thereof and application thereof in flexible laminated solar cell 江汉大学 2024-08-02 CN disclosed
US-20100168167-A1 Piperidinones Useful in the Treatment of Inflammation BIOLIPOX AB (SE) 2010-07-01 US disclosed
US-20100137587-A1 Heterocyclic compound and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED 2010-06-03 US disclosed
EP-2134686-A1 PIPERIDINONES USEFUL IN THE TREATMENT OF INFLAMMATION Biolipox AB (SE) 2009-12-23 EP disclosed
WO-2009080663-A1 TRIAZOLE OXADIAZOLES DERIVATIVES MERCK SERONO S.A. (CH) 2009-07-02 WO disclosed
WO-2008110793-A1 PIPERIDINONES USEFUL IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2008-09-18 WO disclosed
US-20070191389-A1 Biaryl derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-16 US disclosed
CN-1980901-A Biaryl derivatives BANYU PHARMA CO LTD (JP) 2007-06-13 CN disclosed
EP-1764362-A1 BIARYL DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-03-21 EP disclosed
CN-1934094-A Diaryl substituted heterocyclic 5-membered ring derivatives BANYU PHARMA CO LTD (JP) 2007-03-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473263-B2 Bicyclic inhibitors of CBX chromodomains CBX2, CBX3, CBX6 MAPT 4531/4885GAA 4034/4885NPC1 2302/4885
US-20260033119-A1 A PHOTONIC-ORGANIC ELECTROCHEMICAL TRANSISTOR PARN, PARL, KCNN4 MAPT 752/4885GAA 4364/4885NPC1 4450/4885
US-20100168167-A1 Piperidinones Useful in the Treatment of Inflammation ARG1, ARG2, PRMT1 MAPT 3306/4885GAA 4214/4885NPC1 2774/4885
US-12612409-B2 Pyrrolopyrimidines as CFTR potentiators CFTR, CLCN2, SLC26A3 MAPT 4880/4885GAA 2850/4885NPC1 251/4885
US-20070191389-A1 Biaryl derivatives GRM1, GRIN1, GRIN2B MAPT 1892/4885GAA 2964/4885NPC1 1716/4885
US-20100137587-A1 Heterocyclic compound and use thereof REN, AGT, ACE MAPT 4513/4885GAA 825/4885NPC1 3316/4885
US-12466811-B2 Mass spectrometry cleavable heterobifunctional photoactivated cross-linkers JMJD7, DCLRE1A, PTMS MAPT 2399/4885GAA 3599/4885NPC1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.