Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775484 | 0.85 | L3MBTL1 (0.48) | SQORHSP90AA1HSP90AB1ALDH1A1HSD17B10 | |
| SCHEMBL15775449 | 0.85 | L3MBTL1 (0.48) | SQORHSP90AA1HSP90AB1ALDH1A1HSD17B10 | |
| SCHEMBL15775490 | 0.82 | ACP1 (0.46) | SQORACHETDP1PTPN1HSD17B10 | |
| SCHEMBL15775748 | 0.79 | SQOR (0.53) | SQORALDH1A1IDO1HSD17B10KDM4E | |
| SCHEMBL15775364 | 0.78 | ALDH1A1 (0.49) | SQORHSP90AA1HSP90AB1ALDH1A1TDP1 | |
| SCHEMBL15775195 | 0.76 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1ALDH1A1PTPN1CYP1A2 | |
| SCHEMBL15775389 | 0.75 | ESR1 (0.45) | SQORADORA2AALDH1A1HSD17B10ADORA1 | |
| SCHEMBL15775799 | 0.75 | SQOR (0.54) | SQORADORA2AALDH1A1ADORA3GAA | |
| SCHEMBL15775605 | 0.74 | NR1I3 (0.53) | SQORTACR3 | |
| SCHEMBL4822189 | 0.72 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1ACHEADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |