Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775590 | 0.87 | NPC1 (0.49) | NR1I3POLBEIF4EMAPTPIN1 | |
| SCHEMBL15775322 | 0.83 | TDP1 (0.41) | POLBTDP1MAPTALDH1A1MEN1 | |
| SCHEMBL15775231 | 0.83 | SQOR (0.43) | POLBEIF4ETDP1MAPTALDH1A1 | |
| SCHEMBL15775417 | 0.83 | LMNA (0.45) | POLBEIF4EMAPTMEN1KMT2A | |
| SCHEMBL15775280 | 0.82 | ELANE (0.43) | POLBEIF4ETDP1TACR3MAPT | |
| SCHEMBL15776164 | 0.82 | SQOR (0.47) | POLBEIF4ETDP1MAPTALDH1A1 | |
| SCHEMBL15775580 | 0.81 | ALDH1A1 (0.46) | POLBEIF4ECNR2TDP1TACR3 | |
| SCHEMBL15775312 | 0.79 | SQOR (0.44) | POLBEIF4ETDP1MAPTALDH1A1 | |
| SCHEMBL15775543 | 0.79 | LMNA (0.45) | POLBEIF4ETDP1MAPTALDH1A1 | |
| SCHEMBL15775605 | 0.79 | NR1I3 (0.53) | NR1I3TACR3SQORPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |