Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775312 | 0.90 | SQOR (0.44) | SQOREIF4EPOLBABCG2MEN1 | |
| SCHEMBL15775590 | 0.84 | NPC1 (0.49) | SQOREIF4EPOLBABCG2MAPT | |
| SCHEMBL15775156 | 0.83 | NR1I3 (0.48) | SQOREIF4EPOLBMEN1KMT2A | |
| SCHEMBL15775442 | 0.80 | SQOR (0.48) | SQORXDHCTSSCTSKPTGDR | |
| SCHEMBL15775417 | 0.80 | LMNA (0.45) | EIF4EPOLBXDHABCG2MEN1 | |
| SCHEMBL15775280 | 0.79 | ELANE (0.43) | EIF4EPOLBABCG2MEN1KMT2A | |
| SCHEMBL15776164 | 0.79 | SQOR (0.47) | SQOREIF4EPOLBABCG2ACP1 | |
| SCHEMBL15775543 | 0.76 | LMNA (0.45) | EIF4EPOLBMEN1KMT2AACP1 | |
| SCHEMBL15775322 | 0.75 | TDP1 (0.41) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL15775871 | 0.75 | NPC1 (0.45) | SQOREIF4EABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |