SCHEMBL158175

SCHEMBL158175

O=C(O)CNc1ccccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 2/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CDC25A P30304 1/20 0.49
ROCK2 O75116 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
AKR1B10 O60218 1/20 0.47
UGT1A9 O60656 1/20 0.47
TRPA1 O75762 1/20 0.47
ABCB11 O95342 1/20 0.47
MT-CO2 P00403 1/20 0.47
TTR P02766 1/20 0.47
ALB P02768 1/20 0.47
UGT1A6 P19224 1/20 0.47
UGT1A1 P22309 1/20 0.47
PTGS1 P23219 1/20 0.47
CXCR1 P25024 1/20 0.47
ADRA1A P35348 1/20 0.47
PTGS2 P35354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29512015 1.00 CXCL8 (0.54) CXCL8MEN1KMT2ACDC25AROCK2
Ammonia Solution, Strong SCHEMBL23300490 0.98 CXCL8 (0.53) CXCL8MEN1KMT2ACDC25AROCK2
SCHEMBL28306745 0.98 CXCL8 (0.53) CXCL8MEN1KMT2ACDC25AROCK2
Cadaverine Tartrate SCHEMBL29131150 0.90 CXCL8 (0.46) CXCL8MEN1KMT2ACDC25AROCK2
SCHEMBL7362942 0.87 CXCL8 (0.44) CXCL8MEN1KMT2ACDC25AROCK2
SCHEMBL7854767 0.86 HDAC1 (0.50) CXCL8MEN1KMT2ACDC25AROCK2
SCHEMBL5692314 0.85 PARP1 (0.51) CXCL8MEN1KMT2ACDC25ARAB9A
SCHEMBL5842471 0.85 KMT2A (0.58) CXCL8MEN1KMT2ANPC1RAB9A
SCHEMBL29620332 0.84 MEN1 (0.50) CXCL8MEN1KMT2AROCK2NPC1
SCHEMBL28095642 0.83 AGTR1 (0.65) CXCL8MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010755-A O-chlorophenylglycine production process 九江中星医药化工有限公司 2026-05-12 CN claimed
CN-118936155-B Heat exchange equipment applied to production of o-chlorophenylglycine 黑龙江泰纳科技集团股份有限公司 2025-05-09 CN claimed
CN-222709597-U Automatic change chlorobenzene glycine ether production flow and controlling means 湖北阿泰克生物科技股份有限公司 2025-04-04 CN claimed
CN-222678054-U O-chlorobenzene glycine preparation device 抚顺友联科技有限公司 2025-03-28 CN claimed
CN-119075979-A Catalyst for hydrogenation of phenyl derivatives and preparation thereof 厦门嘉氢科技有限公司 2024-12-06 CN claimed
CN-118936155-A Heat exchange equipment applied to production of o-chlorophenylglycine 黑龙江泰纳科技集团股份有限公司 2024-11-12 CN claimed
CN-118359514-A N-ester salicylamide compound and preparation method and application thereof 湖南科技大学 2024-07-19 CN claimed
CN-118325877-A Acylase mutant and application of chemical-enzymatic synthesis of clopidogrel 浙江工业大学 2024-07-12 CN claimed
CN-117964029-B Method for preparing p-chlorophenylglycine based on waste liquid generated in production of chlorfenapyr 内蒙古莱科作物保护有限公司 2024-06-14 CN claimed
CN-118108672-A O-chlorophenylglycine synthesis intermediate and detection method of o-chlorophenylglycine 抚顺顺能化工有限公司 2024-05-31 CN claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
US-20040176637-A1 Process for preparation of 2-chlorophenylglycine derivatives and enantiomerically separation ROBERT C. C. WU (TW) 2004-09-09 US claimed
WO-1998039286-A1 METHOD FOR OBTAINING α-AMINO ACID ENANTIOMERS AND INTERMEDIATE DIASTEREOISOMERIC SALTS SANOFI (FR) 1998-09-11 WO claimed
EP-0442585-B1 Process for racemization of an optically active amino acid amide DSM NV (NL) 1994-07-20 EP claimed
EP-0256971-B1 COLOUR RIBBON FOR DYE TRANSFER BY HEAT REACTION SIEMENS AKTIENGESELLSCHAFT (DE) 1990-05-02 EP claimed
US-4756633-A Inking ribbon including a sublimable release layer for color transfer under the influence of heat DREES FRIEDRICH WILHELM (DE) 1988-07-12 US claimed
EP-0256971-A1 Colour ribbon for dye transfer by heat reaction SIEMENS AKTIENGESELLSCHAFT (DE) 1988-02-24 EP claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176637-A1 Process for preparation of 2-chlorophenylglycine derivatives and enantiomerically separation SRM, CES2, UGT1A6 CXCL8 4470/4885MEN1 4810/4885KMT2A 2170/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 CXCL8 1830/4885MEN1 892/4885KMT2A 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.