Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052818 | 0.79 | TSHR (0.42) | TSHR | |
| SCHEMBL4416159 | 0.76 | TSHR (0.38) | TSHR | |
| SCHEMBL11741110 | 0.76 | TSHR (0.39) | TSHR | |
| SCHEMBL28389135 | 0.74 | DUT (0.37) | TSHR | |
| SCHEMBL18920319 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL31338981 | 0.72 | LOX (0.31) | — | |
| SCHEMBL838422 | 0.72 | ADRB2 (0.38) | TSHR | |
| SCHEMBL8083875 | 0.72 | ADRB2 (0.38) | TSHR | |
| SCHEMBL27738982 | 0.72 | — | — | |
| SCHEMBL27995263 | 0.71 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | claimed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | claimed |
| US-9537052-B2 | Coated phosphors and light emitting devices including the same | CREE, INC. (US) | 2017-01-03 | — | — | US | disclosed |
| EP-2714840-B1 | COATED PHOSPHORS AND LIGHT EMITTING DEVICES INCLUDING THE SAME | CREE INC (US) | 2016-04-13 | — | — | EP | disclosed |
| US-9187501-B2 | Nitric oxide-releasing nanorods and their methods of use | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-11-17 | — | — | US | disclosed |
| US-8981139-B2 | Tertiary S-nitrosothiol-modified nitric—oxide-releasing xerogels and methods of using the same | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140217326-A1 | COATED PHOSPHORS AND LIGHT EMITTING DEVICES INCLUDING THE SAME | CREE, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8729790-B2 | Coated phosphors and light emitting devices including the same | CREE, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20140134321-A1 | NITRIC OXIDE-RELEASING COATINGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-05-15 | — | — | US | disclosed |
| CN-103717701-A | Coated phosphors and light emitting devices including the same | KE RUI | 2014-04-09 | — | — | CN | disclosed |
| WO-2011047013-A1 | NITRIC OXIDE-RELEASING COATINGS | NOVAN, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-20110086234-A1 | NITRIC OXIDE-RELEASING COATINGS | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2011-04-14 | — | — | US | disclosed |
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | disclosed |
| US-20070014828-A1 | Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same | GOVERNMENT OF THE USA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2007-01-18 | — | — | US | disclosed |
| EP-1545798-A4 | CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME | US GOV HEALTH & HUMAN SERV (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1545798-A1 | CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2004012874-A1 | CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | NOS2, NOS1, NOS3 | TSHR 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.