SCHEMBL15856293

SCHEMBL15856293

N#Cc1ccc(N(c2ccccc2)c2cc3c4cc(N(c5ccccc5)c5ccc(C#N)cc5)c5ccccc5c4oc3c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.39
TSHR P16473 1/20 0.36
ABCG2 Q9UNQ0 2/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
MAOB P27338 2/20 0.33
MAOA P21397 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
KDM1A O60341 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
C1R P00736 1/20 0.32
PTGER4 P35408 1/20 0.32
RORC P51449 1/20 0.31
ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15851633 0.92 TNKS (0.41) TNKSTSHRABCG2KEAP1NFE2L2
SCHEMBL15856294 0.91 ALDH1A1 (0.42) TNKSABCG2KEAP1NFE2L2MAOB
SCHEMBL21870294 0.90 PTGDR2 (0.44) TNKSABCG2PTGDR2KDM1A
SCHEMBL15856295 0.88 KDM4E (0.34) TNKSABCG2KEAP1NFE2L2PTGDR2
SCHEMBL15852050 0.87 TNKS (0.34) TNKSTSHRABCG2KEAP1NFE2L2
SCHEMBL10068520 0.86 TSHR (0.42) TNKSTSHRABCG2KEAP1NFE2L2
SCHEMBL15852136 0.86 AHR (0.37) TNKSABCG2NPC1CA1CA2
SCHEMBL14325122 0.85 TNKS (0.46) TNKSABCG2KDM1A
SCHEMBL15856286 0.83 TNKS (0.41) TNKSKEAP1NFE2L2
SCHEMBL15856297 0.83 PRKDC (0.39) TNKSTSHRABCG2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230047477-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230019712-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-19 US disclosed
US-20230020436-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-19 US disclosed
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2023-01-12 US disclosed
US-11552252-B1 2023-01-10 US disclosed
US-20220411437-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-20220285625-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-08 US disclosed
US-20220169656-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2022-06-02 US disclosed
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-01-27 US disclosed
US-10777752-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-09-15 US disclosed
US-10763444-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-09-01 US disclosed
US-10763441-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-09-01 US disclosed
US-20200111973-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-04-09 US disclosed
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 US disclosed
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-11-09 US disclosed
US-9755156-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-09-05 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411437-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS RPS19, TERT, PIEZO1 TNKS 3071/4885TSHR 1172/4885ABCG2 3815/4885
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, ESR1 TNKS 4208/4885TSHR 1561/4885ABCG2 4560/4885
US-20200111973-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, MRPS22 TNKS 4057/4885TSHR 1497/4885ABCG2 4345/4885
US-20220169656-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS RPS19, TERT, PIEZO1 TNKS 3071/4885TSHR 1172/4885ABCG2 3815/4885
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 TNKS 3987/4885TSHR 3155/4885ABCG2 1315/4885
US-10777752-B2 Organic electroluminescence device and electronic apparatus provided with the same RER1, RPS19, MRPS22 TNKS 4057/4885TSHR 1497/4885ABCG2 4345/4885
US-20230020436-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS MRPS22, RER1, EMC2 TNKS 3829/4885TSHR 869/4885ABCG2 4057/4885
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SQOR, AOC1 TNKS 3987/4885TSHR 3155/4885ABCG2 1315/4885
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME RER1, RIF1, RPS19 TNKS 3353/4885TSHR 1089/4885ABCG2 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.