Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 8/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389083 | 0.86 | ALDH1A1 (0.41) | CA12CA1CA2CA9CA3 | |
| SCHEMBL23045338 | 0.78 | GAA (0.42) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL8829563 | 0.75 | HSD11B1 (0.46) | CA1CA2NPC1ALDH1A1HSD11B1 | |
| SCHEMBL18309904 | 0.74 | CA12 (0.53) | CA12CA1CA2CA9GLA | |
| SCHEMBL28217752 | 0.74 | CA12 (0.53) | CA12CA1CA2CA9GLA | |
| SCHEMBL548280 | 0.74 | ESR1 (0.42) | CA12CA1CA2CA9ESR1 | |
| SCHEMBL27898174 | 0.72 | TSHR (0.38) | CA12CA1CA2CA9CA3 | |
| SCHEMBL14647641 | 0.70 | ENPP2 (0.52) | CA12CA1CA2CA9GLA | |
| SCHEMBL21581122 | 0.70 | CA12 (0.48) | CA12CA1CA2CA9GLA | |
| SCHEMBL312518 | 0.70 | HTR6 (0.70) | CA12CA1CA2CA9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771923-B2 | Radiation-sensitive composition | JSR CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |