Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | FCER2 | P06734 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620366 | 0.75 | ALDH1A1 (0.38) | KMT2APOLBNPC1RAB9AKCNH2 | |
| SCHEMBL620367 | 0.75 | ALDH1A1 (0.38) | KMT2APOLBNPC1RAB9AKCNH2 | |
| SCHEMBL31067200 | 0.69 | GAA (0.41) | POLBTP53HTTSMN1; SMN2IDO1 | |
| Hydrochloric Acid SCHEMBL31067225 | 0.68 | GAA (0.40) | POLBROCK2ROCK1PKN2TP53 | |
| SCHEMBL503186 | 0.67 | KIF11 (0.52) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL7350753 | 0.67 | KIF11 (0.52) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL7247505 | 0.66 | MAOA (0.50) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL20393464 | 0.66 | MMP1 (0.48) | MMP1FCER2PTGER1PTGFRPTGER3 | |
| SCHEMBL6703333 | 0.65 | KMT2A (0.53) | KMT2APOLBNPC1RAB9ATP53 | |
| SCHEMBL5031561 | 0.65 | FBP1 (0.48) | MMP1FCER2PTGER1PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927542-B2 | Bicyclic antibiotics | BASILEA PHARMACEUTICA AG (CH) | 2015-01-06 | — | — | US | disclosed |
| US-20140221348-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221348-A1 | NOVEL BICYCLIC ANTIBIOTICS | C1S, XPA, XDH | MMP1 4205/4885FCER2 4775/4885PTGER1 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.